1143623-67-9Relevant articles and documents
Design, synthesis, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase inhibitors
Kono, Mitsunori,Matsumoto, Takahiro,Imaeda, Toshihiro,Kawamura, Toru,Fujimoto, Shinji,Kosugi, Yohei,Odani, Tomoyuki,Shimizu, Yuji,Matsui, Hideki,Shimojo, Masato,Kori, Masakuni
, p. 1468 - 1478 (2014/03/21)
A series of piperazine ureas were designed, synthesized, and evaluated for their potential as novel orally efficacious fatty acid amide hydrolase (FAAH) inhibitors for the treatment of neuropathic and inflammatory pain. We carried out an optimization stud