1144072-40-1 Usage
General Description
The chemical "Urea, N-[4-(4-methyl-1-piperazinyl)phenyl]-N'-[4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-" is a complex organic compound with a molecular structure that includes a urea group, a piperazine ring, and a pyrazolo-pyrimidin-yl group. This chemical is likely a potent bioactive compound with potential pharmaceutical applications, due to the presence of the pyrazolo-pyrimidin-yl group, which is often found in drugs with kinase inhibitor activity. The presence of the piperazine ring and the urea group also suggest that this chemical may have the potential for use as a drug or in medicinal chemistry applications. Further research and evaluation would be needed to understand the specific properties and potential uses of this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 1144072-40-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,4,0,7 and 2 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1144072-40:
(9*1)+(8*1)+(7*4)+(6*4)+(5*0)+(4*7)+(3*2)+(2*4)+(1*0)=111
111 % 10 = 1
So 1144072-40-1 is a valid CAS Registry Number.
1144072-40-1Relevant articles and documents
Incorporation of water-solubilizing groups in pyrazolopyrimidine mTOR inhibitors: Discovery of highly potent and selective analogs with improved human microsomal stability
Richard, David J.,Verheijen, Jeroen C.,Curran, Kevin,Kaplan, Joshua,Toral-Barza, Lourdes,Hollander, Irwin,Lucas, Judy,Yu, Ker,Zask, Arie
scheme or table, p. 6830 - 6835 (2010/07/05)
A series of highly potent and selective pyrazolopyrimidine mTOR inhibitors which contain water-solubilizing groups attached to the 6-arylureidophenyl moiety have been prepared. Such derivatives displayed superior potency to those in which these appendages
