1144500-98-0

Basic information

• Product Name: 1-(2-chloro-6-methyl-pyridine-4-carbonyl)-3-(2,2-difluoro-benzo[1,3]dioxol-5-yl)-thiourea
• CAS NO: 1144500-98-0
• Molecular Weight: 385.779
• Mol File: 1144500-98-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2-chloro-6-methyl-pyridine-4-carbonyl)-3-(2,2-difluoro-benzo[1,3]dioxol-5-yl)-thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-chloro-6-methyl-pyridine-4-carbonyl)-3-(2,2-difluoro-benzo[1,3]dioxol-5-yl)-thiourea(1144500-98-0)
• EPA Substance Registry System: 1-(2-chloro-6-methyl-pyridine-4-carbonyl)-3-(2,2-difluoro-benzo[1,3]dioxol-5-yl)-thiourea(1144500-98-0)

Safety Data

• Hazardous Substances Data: 1144500-98-0(Hazardous Substances Data)

Upstream product

• 1544-85-0 2,2-difluoro-benzo[1,3]dioxol-5-ylamine 

Relevant articles and documents

1,3,5-TRISUBSTITUTED TRIAZOLE DERIVATIVE

The present invention relates to 2-[3-(2,2-Difluoro-benzo[l1,3]dioxol-5-ylamino)-5-(2,6-dimethyl-pyridin-4-yl)-[1,2,4]triazol-1-yl]-N-ethyl-acetamide and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy. The invention particularly relates to a potent positive allosteric modulator of nicotinic acetylcholine receptors which have the capability of increasing the efficacy of nicotinic receptor agonists.