114468-29-0

Basic information

• Product Name: (E)-1-(3,4-dimethoxyphenyl)-N-phenylmethanimine
• Synonyms: (E)-1-(3,4-dimethoxyphenyl)-N-phenylmethanimine
• CAS NO: 114468-29-0
• Molecular Weight: 241.29
• Mol File: 114468-29-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (E)-1-(3,4-dimethoxyphenyl)-N-phenylmethanimine(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(3,4-dimethoxyphenyl)-N-phenylmethanimine(114468-29-0)
• EPA Substance Registry System: (E)-1-(3,4-dimethoxyphenyl)-N-phenylmethanimine(114468-29-0)

Safety Data

• Hazardous Substances Data: 114468-29-0(Hazardous Substances Data)

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 62-53-3 aniline 

Downstream Products

• 82363-30-2 N-(3,4-dimethoxybenzyl)benzeneamine 
• 74478-19-6 1,2-Bis-(3,4-dimethoxy-phenyl)-N,N'-diphenyl-ethane-1,2-diamine 
• 78878-14-5 3-Benzyloxy-4-(3,4-dimethoxy-phenyl)-1-phenyl-azetidin-2-one 
• 75957-80-1 N-phenyl-2-amino-3-(3,4-dimethoxyphenyl)propionamide 

Relevant articles and documents

Synthesis of chromeno[3,4-b]piperazines by an enol-ugi/reduction/cyclization sequence

Keto piperazines and aminocoumarins are privileged building blocks for the construction of geometrically constrained peptides and therefore valuable structures in drug discovery. Combining these two heterocycles provides unique rigid polycyclic peptidomimetics with drug-like properties including many points of diversity that could be modulated to interact with different biological receptors. This work describes an efficient multicomponent approach to condensed chromenopiperazines based on the novel enol-Ugi reaction. Importantly, this strategy involves the first reported post-condensation transformation of an enol-Ugi adduct.

Highly stereoselective reactions of γ-sulfinyl carbanions with achiral imines

Lithium 2-p-tolylsulfinylbenzyl carbanions react with different N-substituted imines affording 1,2-diaryl ethyl (and propyl) amines with a high stereoselectivity control at both benzyllic (only dependent of the sulfur configuration) and iminic carbons. The anti:syn ratio, ranging between >96:98, dependent on the electronic density at nitrogen. Copyright Taylor & Francis Inc.