114554-95-9Relevant articles and documents
Studies toward the structural optimization of novel thiazolylhydrazone- based potent antitrypanosomal agents
Hernandes, Marcelo Zaldini,Rabello, Marcelo Montenegro,Leite, Ana Cristina Lima,Cardoso, Marcos Veríssimo Oliveira,Moreira, Diogo Rodrigo Magalhaes,Brondani, Dalci José,Simone, Carlos Alberto,Reis, Luiza Campos,Souza, Marina Assis,Pereira, Valéria Rego Alves,Ferreira, Rafaela Salgado,McKerrow, James Hobson
experimental part, p. 7826 - 7835 (2011/02/22)
In previous studies, we identified promising anti-Trypanosoma cruzi cruzain inhibitors based on thiazolylhydrazones. To optimize this series, a number of medicinal chemistry directions were explored and new thiazolylhydrazones and thiosemicarbazones were
