114576-86-2 Usage
Description
4-[(1Z)-1-pyridin-2-yl-3-pyrrolidin-1-ylprop-1-en-1-yl]phenylmethanol is a complex organic chemical compound characterized by its unique molecular structure. It consists of a phenyl ring connected to a pyridine and a pyrrolidinylpropenyl group, with a methanol functional group attached to the phenyl ring. 4-[(1Z)-1-pyridin-2-yl-3-pyrrolidin-1-ylprop-1-en-1-yl]phenylmethanol may hold potential applications in various sectors, such as pharmaceuticals, organic synthesis, and material science. However, further research is necessary to comprehensively understand its properties and possible uses.
Uses
Used in Pharmaceutical Applications:
4-[(1Z)-1-pyridin-2-yl-3-pyrrolidin-1-ylprop-1-en-1-yl]phenylmethanol is used as a chemical intermediate for the development of novel pharmaceutical compounds. Its unique molecular structure may contribute to the creation of new drugs with specific therapeutic properties.
Used in Organic Synthesis:
In the field of organic synthesis, 4-[(1Z)-1-pyridin-2-yl-3-pyrrolidin-1-ylprop-1-en-1-yl]phenylmethanol can be utilized as a building block for the synthesis of more complex organic molecules. Its versatile structure allows for further functionalization and modification, leading to the development of new compounds with potential applications in various industries.
Used in Material Science:
4-[(1Z)-1-pyridin-2-yl-3-pyrrolidin-1-ylprop-1-en-1-yl]phenylmethanol may also find applications in material science, where its unique structure could be exploited to create new materials with specific properties. These materials could potentially be used in various applications, such as in the development of advanced coatings, sensors, or other high-tech applications.
Check Digit Verification of cas no
The CAS Registry Mumber 114576-86-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,5,7 and 6 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 114576-86:
(8*1)+(7*1)+(6*4)+(5*5)+(4*7)+(3*6)+(2*8)+(1*6)=132
132 % 10 = 2
So 114576-86-2 is a valid CAS Registry Number.
114576-86-2Relevant articles and documents
Microbial transformation of the antihistaminic drug triprolidine hydrochloride
Hansen Jr.,Heflich,Korfmacher,Miller,Cerniglia
, p. 259 - 264 (2007/10/02)
The production of a known mammalian metabolite of the antihistamine triprolidine through fungal metabolic transformation has been demonstrated. The filamentous fungus Cunninghamella elegans ATCC 9245 was grown in Sabouraud dextrose broth containing triprolidine hydrochloride monohydrate. One major metabolite was extracted with methylene chloride, isolated by high-performance liquid chromatography, and identified by its proton-nuclear magnetic resonance and desorption chemical ionization mass spectral properties as hydroxymethyl triprolidine (2-[1-(4-hydroxymethylphenyl)-3-(1-pyrrolidinyl-1-propenyl)] pyridine). After 240 h of incubation, the hydroxymethyl derivative represented ~55.0% of the initial dose. Fungal oxidation of hydroxymethyl triprolidine to the corresponding carboxylic acid triprolidine derivative (also a known mammalian triprolidine metabolite) was not observed. No mutagenic activity was observed for triprolidine and hydroxymethyl triprolidine by reversion of Salmonella typhimurium strains TA97, TA98, TA100, and TA104 at concentrations up to 1000 and 200 μg/plate, respectively. These results suggest that the fungal metabolism of triprolidine to the hydroxymethyl derivative occurs predominantly through pathways which do not result in mutagenic activation. Incubation of C. elegans with triprolidine under an 18O2 atmosphere and subsequent electron impact mass spectral analysis of the hydroxymethyl triprolidine formed indicate that molecular oxygen was incorporated into the methyl group and suggest a mono-oxygenase catalyzed reaction. This study parallels previous studies on the mammalian metabolism of triprolidine and clearly indicates that the microbial transformation of triprolidine is a useful alternative for the synthesis of potential mammalian metabolites.
