1146-84-5

Basic information

• Product Name: Methanone, (4-methylphenyl)(2,4,6-trimethylphenyl)-
• CAS NO: 1146-84-5
• Molecular Formula: C17H18O
• Molecular Weight: 238.329
• Mol File: 1146-84-5.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Methanone, (4-methylphenyl)(2,4,6-trimethylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (4-methylphenyl)(2,4,6-trimethylphenyl)-(1146-84-5)
• EPA Substance Registry System: Methanone, (4-methylphenyl)(2,4,6-trimethylphenyl)-(1146-84-5)

Safety Data

• Hazardous Substances Data: 1146-84-5(Hazardous Substances Data)

Upstream product

• 874-60-2 4-methyl-benzoyl chloride 
• 108-67-8 1,3,5-trimethyl-benzene 
• 487-68-3 mesytaldehyde 
• 106-38-7 para-bromotoluene 
• 99-75-2 4-methyl-benzoic acid methyl ester 
• 6140-17-6 4-methylbenzotrifluoride 
• 624-31-7 4-tolyl iodide 
• 3112-46-7 mesitylglyoxylic acid 
• 1033133-21-9 potassium 2-oxo-2-(2,4,6-trimethylphenyl)acetate 
• 480-63-7 mesitylenecarboxylic acid 
• 108-88-3 toluene 
• 99-94-5 p-Toluic acid 

Downstream Products

• 42467-11-8 2,4,4',6-Tetramethylbenzhydrol 
• 1146-87-8 2,4,4',6-Tetramethyl-thiobenzophenon 
• 612824-37-0 1-(4-methylphenyl)-1-(2,4,6-trimethylphenyl)ethene 

Relevant articles and documents

Self-Assembled 2,3-Dicyanopyrazino Phenanthrene Aggregates as a Visible-Light Photocatalyst

In this study, 2,3-dicyanopyrazino phenanthrene (DCPP), a commodity chemical that can be prepared at an industrial scale, was used as a photocatalyst in lieu of Ru or Ir complexes in C-X (X = C, N, and O) bond-forming reactions under visible-light irradiation. In these reactions, [DCPP]n aggregates were formed in situ through physical π-πstacking of DCPP monomers in organic solvents. These aggregates exhibited excellent photo- and electrochemical properties, including a visible light response (430 nm), long excited-state lifetime (19.3 μs), high excited-state reduction potential (Ered([DCPP]n*/[DCPP]n·-) = +2.10 V vs SCE), and good reduction stability. The applications of [DCPP]n aggregates as a versatile visible-light photocatalyst were demonstrated in decarboxylative C-C cross-coupling, amidation, and esterification reactions.

Merging Photoredox and Nickel Catalysis: The Direct Synthesis of Ketones by the Decarboxylative Arylation of α-Oxo Acids

The direct decarboxylative arylation of α-oxo acids has been achieved by synergistic visible-light-mediated photoredox and nickel catalysis. This method offers rapid entry to aryl and alkyl ketone architectures from simple α-oxo acid precursors via an acyl radical intermediate. Significant substrate scope is observed with respect to both the oxo acid and arene coupling partners. This mild decarboxylative arylation can also be utilized to efficiently access medicinal agents, as demonstrated by the rapid synthesis of fenofibrate. The direct decarboxylative arylation of α-oxo acids has been achieved by synergistic visible-light-mediated photoredox and nickel catalysis. This method offers rapid entry to aryl and alkyl ketone architectures from simple α-oxo acid precursors via an acyl radical intermediate. Significant substrate scope is observed with respect to both the oxo acid and arene coupling partners.

Synthesis of Diverse Aromatic Ketones through C?F Cleavage of Trifluoromethyl Group

An efficient synthetic method of aromatic ketones through C?F cleavage of trifluoromethyl group is disclosed. The high functional group tolerance of the transformation and the remarkable stability of trifluoromethyl group in various reactions enabled mult