114650-49-6

Basic information

• Product Name: 4-amino-3-octylphenol
• CAS NO: 114650-49-6
• Molecular Weight: 221.343
• Mol File: 114650-49-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-amino-3-octylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-3-octylphenol(114650-49-6)
• EPA Substance Registry System: 4-amino-3-octylphenol(114650-49-6)

Safety Data

• Hazardous Substances Data: 114650-49-6(Hazardous Substances Data)

Upstream product

• 1014-66-0 trimethyl(4-nitrophenoxy)silane 
• 38841-98-4 n-octylmagnesium chloride 

Relevant articles and documents

ONE-POT CHEMOSELECTIVE REDUCTIVE ALKYLATION OF NITROARENES: A NEW GENERAL METHOD OF SYNTHESIS OF ALKYLANILINES.

A New facile and general synthesis of alkylanilines by one-pot reductive alkylation of nitroarenes is reported.This method is based on the "in situ" reduction by hydrides (LiAlH4 or NaBH4) in the presence of catalytic amounts of Pd/C, of nitronate adducts arising from the conjugate addition of Grignard reagents to mononitroarenes.LiAlH4 showed to be a more efficient but less selective reducing agent than NaBH4.The reaction can be successfully applied to mono, homo and hetero bicyclic systems and allows to introduce a large variety of alkyl chains without isomerisation phenomena.