1146543-05-6

Basic information

• Product Name: 4-(4-methoxy-phenyl)-pyrrolo[1,2-a]quinoline
• Synonyms: 4-(4-methoxy-phenyl)-pyrrolo[1,2-a]quinoline
• CAS NO: 1146543-05-6
• Molecular Weight: 273.334
• Mol File: 1146543-05-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-(4-methoxy-phenyl)-pyrrolo[1,2-a]quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-methoxy-phenyl)-pyrrolo[1,2-a]quinoline(1146543-05-6)
• EPA Substance Registry System: 4-(4-methoxy-phenyl)-pyrrolo[1,2-a]quinoline(1146543-05-6)

Safety Data

• Hazardous Substances Data: 1146543-05-6(Hazardous Substances Data)

Upstream product

• 615-36-1 2-bromoaniline 
• 583-55-1 1-Bromo-2-iodobenzene 
• 69907-27-3 1-(2-bromophenyl)-1H-pyrrole 
• 768-60-5 4-methoxyphenylacetylen 
• 157017-41-9 1-(2-iodo-phenyl)-1H-pyrrole 
• 1311312-20-5 1-(2-((4-methoxyphenyl)ethynyl)phenyl)-1H-pyrrole 
• 1311312-38-5 5-iodo-4-(4-methoxyphenyl)pyrrolo[1,2-a]quinoline 
• 1146543-04-5 1-[2-(2,2-dibromo-vinyl)-phenyl]-1H-pyrrole 
• 5720-07-0 4-methoxyphenylboronic acid 

Relevant articles and documents

Synthesis of pyrrolo[1,2-a] quinolines and ullazines by visible light mediated one- and twofold annulation of N-arylpyrroles with arylalkynes

1-(2-Bromophenyl)-1H-pyrrole and 1-(2,6-dibromophenyl)-1H-pyrrole react in the presence of catalytic amounts of rhodamine 6G (Rh-6G) and N,N-diisopropylethylamine (DIPEA) under blue light irradiation with aromatic alkynes and subsequently cyclize intramol

Synthesis of 5-iodopyrrolo[1,2- a ]quinolines and indolo[1,2- a ]quinolines via iodine-mediated electrophilic and regioselective 6- endo - Dig ring closure

The endo-cyclic ring closure of 1-(2-(substituted ethynyl)phenyl)-1H- pyrroles 3-t and 1-(2-(substituted ethynyl)phenyl)-H-indole 4-o mediated by Lewis acid (I2) under mild conditions afforded substituted 5-iodopyrrolo[1,2-a]quinolines 5-t and 5-iodoindolo[1,2-a]quinolines 6-o in good to excellent yields. The reaction shows selective C - C bond formation on the more electrophilic alkynyl carbon, resulting in the regioselective 6-endo-dig-cyclized product. Iodo derivatives of pyrrolo- and indoloquinolines allow functional group diversification on the quinoline nucleus, which proves to be highly advantageous for structural and biological activity assessments.