114663-05-7Relevant articles and documents
Introduction of Functionalized C1, C2, and C3 Units to Imines through the Dimethylzinc-Air-Initiated Radical Addition
Yamada, Ken-Ichi,Yamamoto, Yasutomo,Maekawa, Masaru,Tomioka, Kiyoshi
, p. 1531 - 1534 (2004)
Introduction of functionalized C1, C2, and C3 units to imines was achieved by using the dimethylzinc-air-initiated α-alkoxyalkyl radical addition as a key reaction. The addition to a C= N double bond chemoselectively occurred in the presence of a C=O doub
A tandem process for the synthesis of β-aminoboronic acids from aziridines with haloamine intermediates
Park, Subin,Koo, Jangwoo,Kim, Weonjeong,Lee, Hong Geun
, p. 3767 - 3770 (2022/04/07)
An unprecedented synthetic strategy is devised to generate β-aminoboronic acids from aziridines via a sequential process involving 1,2-iodoamine formation and radical borylation under light irradiation. A variety of aziridines including multiply substituted aziridines have been successfully employed as synthetic precursors, expanding their synthetic utility compared to previous methods. Mechanistic studies suggest that the boron source plays a unique role in the borylation step, and in the formation of haloamine intermediates.
A One-Pot Reaction toward the Diastereoselective Synthesis of Substituted Morpholines
Aubineau, Thomas,Cossy, Janine
supporting information, p. 7419 - 7423 (2018/12/11)
The diastereoselective synthesis of various substituted morpholines has been achieved from vinyloxiranes and amino-alcohols under sequential Pd(0)-catalyzed Tsuji-Trost/Fe(III)-catalyzed heterocyclization. Using the same strategy, 2,6-, 2,5-, and 2,3-disubstituted as well as 2,5,6- and 2,3,5-trisubstituted morpholines were obtained in good to excellent yields and diastereoselectivities.
Efficient and regioselective ring-opening of arylaziridines with alcohols, thiols, amines and N-heteroaromatic compounds using sulphated zirconia
Llaveria, Josep,Espinoza, Araceli,Negrón, Guillermo,Isabel Matheu,Castillón, Sergio
supporting information; experimental part, p. 2525 - 2529 (2012/06/18)
Sulphated zirconia is an efficient catalyst for the regioselective ring-opening of aryl-substituted aziridines. This heterogeneous catalyst can be used several times without loss of activity and is compatible with a variety of acid sensitive and slightly basic nucleophiles.