1146757-92-7 Usage
Description
1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carboxylic acid is a complex organic compound characterized by its unique molecular structure. It features a quinoline ring connected to a pyrazole ring, with the latter being further attached to a carboxylic acid group. Additionally, the presence of a chloro group on the quinoline ring and two methoxy groups on the phenyl ring contribute to its distinct chemical properties. This diversity in its structure suggests potential pharmaceutical applications, which would require further research and testing to confirm.
Uses
Used in Pharmaceutical Industry:
1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carboxylic acid is used as a potential pharmaceutical compound for its diverse chemical structure. The presence of various functional groups, such as the quinoline ring, pyrazole ring, carboxylic acid group, chloro group, and methoxy groups, may impart specific biological activities that could be harnessed for therapeutic purposes. Further research and testing are necessary to determine the specific properties and potential uses of this chemical in the pharmaceutical industry.
Used in Drug Development:
1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carboxylic acid is used as a starting material or a building block in the development of new drugs. Its unique molecular structure may provide a foundation for the creation of novel therapeutic agents with specific targeting capabilities or enhanced pharmacological properties. 1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carboxylic acid's potential applications in drug development could be explored through medicinal chemistry and pharmacological studies.
Used in Chemical Research:
1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carboxylic acid is used as a subject of study in chemical research. Its complex structure and the presence of multiple functional groups make it an interesting candidate for investigating various chemical reactions, synthesis pathways, and the development of new synthetic methods. Understanding the reactivity and properties of this compound can contribute to the advancement of organic chemistry and the discovery of new chemical entities with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 1146757-92-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,6,7,5 and 7 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1146757-92:
(9*1)+(8*1)+(7*4)+(6*6)+(5*7)+(4*5)+(3*7)+(2*9)+(1*2)=177
177 % 10 = 7
So 1146757-92-7 is a valid CAS Registry Number.
1146757-92-7Relevant articles and documents
A Machine-assisted flow synthesis of SR48692: A probe for the investigation of neurotensin receptor-1
Battilocchio, Claudio,Deadman, Benjamin J.,Nikbin, Nikzad,Kitching, Matthew O.,Baxendale, Ian R.,Ley, Steven V.
, p. 7917 - 7930 (2013)
Here we report the direct comparison of a conventional batch mode synthesis of Meclinertant (SR48692, 1), a neurotensin receptor-1 antagonist, with its machine-assisted flow chemistry alternative. By using these enabling tools, combined with solid-supported reagents and scavengers, many process advantages were observed. Care, however, must be taken not to convert these techniques into expensive solutions to problems that do not exist. Copyright
Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3- yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound
Thomas, James B.,Giddings, Angela M.,Wiethe, Robert W.,Olepu, Srinivas,Warner, Keith R.,Sarret, Philippe,Gendron, Louis,Longpre, Jean-Michel,Zhang, Yanan,Runyon, Scott P.,Gilmour, Brian P.
, p. 5318 - 5332 (2014/07/08)
Compounds active at neurotensin receptors (NTS1 and NTS2) exert analgesic effects on different types of nociceptive modalities, including thermal, mechanical, and chemical stimuli. The NTS2 preferring peptide JMV-431 (2) and the NTS2 selective nonpeptide compound levocabastine (6) have been shown to be effective in relieving the pain associated with peripheral neuropathies. With the aim of identifying novel nonpeptide compounds selective for NTS2, we examined analogues of SR48692 (5a) using a FLIPR calcium assay in CHO cells stably expressing rat NTS2. This led to the discovery of the NTS2 selective nonpeptide compound 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl] carbonyl}amino)cyclohexane carboxylic acid (NTRC-739, 7b) starting from the nonselective compound 5a.
