1146852-39-2Relevant articles and documents
Synthesis, characterization, and biological assessment of the four stereoisomers of the H3 receptor antagonist 5-fluoro-2-methyl-N-[2- methyl-4-(2-methyl[1,3′]bipyrrolidinyl-1′-yl)phenyl]benzamide
Gao, Zhongli,Hurst, William J.,Guillot, Etienne,Nagorny, Raisa,Pruniaux, Marie-Pierre,Hendrix, James A.,George, Pascal G.
, p. 4044 - 4047 (2013/07/25)
This Letter describes the asymmetric synthesis of the four stereoisomers (8a-8d) of a potent and highly selective histamine H3 receptor (H3R) antagonist, 5-fluoro-2-methyl-N-[2-methyl-4-(2-methyl[1, 3′]bipyrrolidinyl-1′-yl) phenyl]be