1147130-24-2

Basic information

• Product Name: C₂₈H₃₉NO₆S
• Synonyms: C₂₈H₃₉NO₆S
• CAS NO: 1147130-24-2
• Molecular Weight: 517.687
• Mol File: 1147130-24-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₈H₃₉NO₆S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₃₉NO₆S(1147130-24-2)
• EPA Substance Registry System: C₂₈H₃₉NO₆S(1147130-24-2)

Safety Data

• Hazardous Substances Data: 1147130-24-2(Hazardous Substances Data)

Upstream product

• 1147130-26-4 C₂₂H₃₃NO₃ 
• 1091627-89-2 (R)-tert-butyl 6,7-dimethoxy-1-(5-methyl-3-methylene-2-oxohexyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1091627-85-8 C₂₄H₃₇NO₅ 
• 1026016-83-0 ((3R,11bR)-3-isobutyl-9.10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one) 
• 1147130-23-1 hydroxyethyl DTBZ ether 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant articles and documents

INTERMEDIATES FOR FLUORINATED DIHYDROTETRABENAZINE ETHER IMAGING AGENTS AND PROBES

The present invention provides novel fluorophilic compounds having structure VI wherein R1 is a C2-C20 aliphatic, a C3-C20 cycloaliphatic, or a C3-C20 aromatic radical comprising at least one functional group susceptible to reaction with nucleophilic fluoride ion or an electrophilic fluorinating agent; R2 is a C1-C10 aliphatic radical, or a C3-C10 cycloaliphatic radical; R3 is hydrogen or a C1-C10 aliphatic radical; and R4 is hydrogen or a C1-C10 aliphatic radical. The fluorophilic compounds are provided in both racemic and enantiomerically enriched forms and are useful as intermediates in the preparation of novel PET imaging agents and probes useful in the discovery and performance assessment of PET imaging agents. The fluorophilic compounds are particularly useful in the preparation of PET imaging agents and probes having a high affinity for VMAT-2, a biomarker implicated in human diabetes and other illnesses such as Parkinson's disease.