114736-31-1

Basic information

• Product Name: 5-bromo-1,1-diphenylpentan-1-ol
• Synonyms: 5-bromo-1,1-diphenylpentan-1-ol
• CAS NO: 114736-31-1
• Molecular Weight: 319.241
• Mol File: 114736-31-1.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 5-bromo-1,1-diphenylpentan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-1,1-diphenylpentan-1-ol(114736-31-1)
• EPA Substance Registry System: 5-bromo-1,1-diphenylpentan-1-ol(114736-31-1)

Safety Data

• Hazardous Substances Data: 114736-31-1(Hazardous Substances Data)

Upstream product

• 108-86-1 bromobenzene 
• 14660-52-7 ethyl 5-bromovalerate 
• 100-58-3 phenylmagnesium bromide 
• 4509-90-4 5-bromovaleroyl chloride 
• 110-52-1 1,4-dibromo-butane 
• 201230-82-2 carbon monoxide 
• 591-51-5 phenyllithium 
• 2067-33-6 5-bromopentanoic acid 

Downstream Products

• 1434533-55-7 (S)-(+)-2-(methoxydiphenylmethyl)tetrahydrothiophene 
• 1434533-59-1 (S)-(+)-(diphenyl(tetrahydrothiophen-2-yl)methoxy)trimethylsilane 
• 1434533-61-5 (S)-(+)-2-((benzyloxy)diphenylmethyl)tetrahydrothiophene 
• 1434533-51-3 (R)-(+)-3-(3-bromopropyl)-2,2-diphenyloxirane 
• 1434533-53-5 (S)-diphenyl(tetrahydrothiophen-2-yl)methanol 
• 118970-95-9 (S)-1-benzyl-2-(hydroxydiphenylmethyl)pyrrolidine 
• 114736-38-8 1,1-diphenyl-5-pyrrolidinepentanol 
• 247118-11-2 N,N-diethyl-5,5-diphenylpent-4-en-1-amine 
• 1501972-44-6 N,N,N-trimethyl-N-(5,5-diphenylpent-4-en-1-yl)ammonium iodide 
• 1501972-43-5 N-chloromethyl-N,N-dimethyl-N-(5,5-diphenylpent-4-en-1-yl)ammonium iodide 
• 1501972-42-4 N-iodomethyl-N,N-dimethyl-N-(5,5-diphenyl-4-penten-1-yl)ammonium iodide 
• 1265145-11-6 1-hydroxy-1-methyl-6,6-diphenyl-5-hexenyl radical 
• 1265145-18-3 2-hydroxy-2-methyl-7,7-diphenylhept-6-enoic acid 

Relevant articles and documents

(Thiolan-2-yl)diphenylmethyl benzyl ether/N,N′-diarylurea cocatalyzed asymmetric aziridination of cinnamyl bromide and aryl aldimine

A dual catalyst system using THT-based chiral sulfide 2a and H-bond donor 10a was developed for the asymmetric imino Corey-Chaykovsky reaction. Under the optimum reaction conditions, cinnamyl bromide reacted with a wide scope of N-diphenylphosphinic aldim

Contra-thermodynamic Hydrogen Atom Abstraction in the Selective C-H Functionalization of Trialkylamine N-CH3 Groups

We report a simple one-pot protocol that affords functionalization of N-CH3 groups in N-methyl-N,N-dialkylamines with high selectivity over N-CH2R or N-CHR2 groups. The radical cation DABCO+?, prepared in situ by oxidation of DABCO with a triarylaminium salt, effects highly selective and contra-thermodynamic C-H abstraction from N-CH3 groups. The intermediates that result react in situ with organometallic nucleophiles in a single pot, affording novel and highly selective homologation of N-CH3 groups. Chemoselectivity, scalability, and recyclability of reagents are demonstrated, and a mechanistic proposal is corroborated by computational and experimental results. The utility of the transformation is demonstrated in the late-stage site-selective functionalization of natural products and pharmaceuticals, allowing rapid derivatization for investigation of structure-activity relationships.

Enantioselective synthesis of diaryl aziridines using tetrahydrothiophene- based chiral sulfides as organocatalysts

This work describes catalytic and asymmetric aziridinations (15 examples, 95-98% ee) of benzyl bromide and imines via the imino Corey-Chaykovsky reaction using (thiolan-2-yl)diarylmethanol benzyl ether as an organocatalyst. The catalyst and analogues thereof were prepared through an expeditious and efficient synthetic route featuring a double nucleophilic substitution and Shi epoxidation as key steps.