114738-93-1

Basic information

• Product Name: (+/-)-2-(2,3,5,6,7,8-Hexahydro-5-oxo-1-phenylthio-6-indolizinyl)-1H-isoindol-1,3(2H)-dion
• CAS NO: 114738-93-1
• Molecular Weight: 390.463
• Mol File: 114738-93-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+/-)-2-(2,3,5,6,7,8-Hexahydro-5-oxo-1-phenylthio-6-indolizinyl)-1H-isoindol-1,3(2H)-dion(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-2-(2,3,5,6,7,8-Hexahydro-5-oxo-1-phenylthio-6-indolizinyl)-1H-isoindol-1,3(2H)-dion(114738-93-1)
• EPA Substance Registry System: (+/-)-2-(2,3,5,6,7,8-Hexahydro-5-oxo-1-phenylthio-6-indolizinyl)-1H-isoindol-1,3(2H)-dion(114738-93-1)

Safety Data

• Hazardous Substances Data: 114738-93-1(Hazardous Substances Data)

Upstream product

• 50-35-1 thalidomide 
• 58992-26-0 1-Phenylthiocyclopropyltriphenylphosphonium-tetrafluoroborat 

Relevant articles and documents

Diastereoselective Syntheses of rac-Slaframine and rac-6-epi-Slaframine

Indolizidinones 8 have been obtained from thalidomide (5) and cyclopropylphosphonium salts 6 in good yields.Acid-catalyzed rearrangement of 8a gave the isomer 11.A regio- and stereoselective acetoxylation of 8a and 11 was achieved with lead tetraacetate: using standard conditions, acetates 15 and 16 were obtained; in the presence of triethylamine, however, 8a has been transformed into the acetoxy derivative 17. rac-6-epi-Slaframine (4) and rac-slaframine (1) were obtained from acetates 16 and 17 on conventional routes.