1147391-02-3 Usage
Description
(R)-4-(4-chlorophenyl)oxazolidin-2-one is a chiral chemical compound belonging to the class of oxazolidinones. It features a three-membered oxazolidin-2-one ring with a 4-chlorophenyl group attached. (R)-4-(4-chlorophenyl)oxazolidin-2-one has been studied for its potential pharmaceutical properties, such as antibacterial and antifungal activities, and is also utilized as a chiral building block in organic synthesis for the production of chiral drugs and pharmaceuticals. Furthermore, it has been investigated for its potential use in asymmetric catalysis and as a ligand in metal-catalyzed reactions, showcasing promise in both medicinal and synthetic chemistry applications.
Uses
Used in Pharmaceutical Industry:
(R)-4-(4-chlorophenyl)oxazolidin-2-one is used as an active pharmaceutical ingredient for its antibacterial and antifungal properties, targeting various pathogens and contributing to the development of new treatments for infectious diseases.
Used in Organic Synthesis:
(R)-4-(4-chlorophenyl)oxazolidin-2-one is used as a chiral building block in the synthesis of chiral drugs and pharmaceuticals, playing a crucial role in the development of enantiomerically pure compounds with improved therapeutic effects and reduced side effects.
Used in Asymmetric Catalysis:
(R)-4-(4-chlorophenyl)oxazolidin-2-one is used as a ligand in metal-catalyzed reactions, enhancing the selectivity and efficiency of asymmetric catalysis processes, which are essential for the production of enantiomerically pure compounds in the pharmaceutical and chemical industries.
Used in Research and Development:
(R)-4-(4-chlorophenyl)oxazolidin-2-one is used as a research compound for exploring its potential applications in various fields, including medicinal chemistry, synthetic chemistry, and materials science, contributing to the advancement of scientific knowledge and the development of innovative technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 1147391-02-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,7,3,9 and 1 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1147391-02:
(9*1)+(8*1)+(7*4)+(6*7)+(5*3)+(4*9)+(3*1)+(2*0)+(1*2)=143
143 % 10 = 3
So 1147391-02-3 is a valid CAS Registry Number.
1147391-02-3Relevant articles and documents
Stereoselective Synthesis of Enantiopure Oxazolidinones via Biocatalytic Asymmetric Aminohydroxylation of Alkenes
Zhou, Xiao-Ying,Wan, Nan-Wei,Li, Ying-Na,Ma, Ran,Cui, Bao-Dong,Han, Wen-Yong,Chen, Yong-Zheng
, p. 4343 - 4348 (2021)
Chiral oxazolidinones are of significance in both medicinal and synthetic chemistry, while preparing these compounds usually involves using expensive starting materials and harsh reaction conditions. Herein, a one-pot biocatalytic cascade process was developed for stereo- and regioselective aminohydroxylation of diverse alkenes by combining styrene monooxygenase and halohydrin dehalogenase, providing an approach to enantiopure oxazolidinones. (Figure presented.).
BIPHENYL DERIVATIVES AS MODULATORS OF THE HISTAMINE-H3 RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
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Page/Page column 43, (2009/06/27)
Biphenyl derivatives of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the H3 histamine receptor. (Ia) Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of histamine H3-associated disorders, such as cognitive disorders, epilepsy, brain trauma, depression, obesity, disorders of sleep and wakefulness, such as narcolepsy, shift-work syndrome, drowsiness as a side effect from a medication, maintenance of vigilance to aid in completion of tasks and the like, cataplexy, hypersomnia, somnolence syndrome, jet lag, sleep apnea and the like, attention deficit hyperactivity disorder (ADHD), schizophrenia, allergies, allergic responses in the upper airway, allergic rhinitis, nasal congestion, dementia, Alzheimer's disease, pain and the like.