1147397-43-0

Basic information

• Product Name: 2-{4-[4-((R)-1-hydroxymethyl-2-methylpropylamino)-5-oxo-6,7-dihydro-5H-5λ4-thieno[3,2-d]pyrimidin-2-yl]piperazin-1-yl}-benzonitrile
• Synonyms: 2-{4-[4-((R)-1-hydroxymethyl-2-methylpropylamino)-5-oxo-6,7-dihydro-5H-5λ4-thieno[3,2-d]pyrimidin-2-yl]piperazin-1-yl}-benzonitrile
• CAS NO: 1147397-43-0
• Molecular Weight: 440.569
• Mol File: 1147397-43-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{4-[4-((R)-1-hydroxymethyl-2-methylpropylamino)-5-oxo-6,7-dihydro-5H-5λ4-thieno[3,2-d]pyrimidin-2-yl]piperazin-1-yl}-benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{4-[4-((R)-1-hydroxymethyl-2-methylpropylamino)-5-oxo-6,7-dihydro-5H-5λ4-thieno[3,2-d]pyrimidin-2-yl]piperazin-1-yl}-benzonitrile(1147397-43-0)
• EPA Substance Registry System: 2-{4-[4-((R)-1-hydroxymethyl-2-methylpropylamino)-5-oxo-6,7-dihydro-5H-5λ4-thieno[3,2-d]pyrimidin-2-yl]piperazin-1-yl}-benzonitrile(1147397-43-0)

Safety Data

• Hazardous Substances Data: 1147397-43-0(Hazardous Substances Data)

Upstream product

• 74901-69-2 2,4-dichloro-6,7-dihydro-thieno[3,2-d]pyrimidine 
• 4276-09-9 (R)-2-amino-3-methylbutanol 
• 1143575-83-0 (R)-2-(2-chloro-5-oxo-6,7-dihydro-5H-5λ⁴-thieno[3,2-d]pyrimidin-4-ylamino)-3-methyl-butan-1-ol 
• 111373-03-6 2-(piperazin-1-yl)benzonitrile 

Relevant articles and documents

NOVEL PHENYL-SUBSTITUTED PIPERAZINO-DIHYDROTHIENOPYRIMIDINES

The invention relates to novel dihydrothienopyrimidines of the formula 1, and to pharmacologically acceptable salts thereof, formula (1) in which X is SO or SO2, but preferably SO, and either R3 is a monosubstituted phenyl ring in the ortho position or in the meta position, or R3 is a phenyl ring bisubstituted in any positions, and pharmaceutical compositions which comprise these compounds. These novel dihydrothienopyrimidines are suitable for the treatment of respiratory or gastrointestinal symptoms or disorders, inflammatory disorders of the joints, of the skin or of the eyes, disorders of the peripheral or central nervous system or cancers.