1147557-97-8 Usage
Description
tert-butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate is a chemical compound that serves as an important intermediate in the synthesis of various pharmaceuticals. It is characterized by its unique molecular structure, which includes a spiro-linked azaspiroheptane core and a carboxylate group. tert-butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate is known for its potential applications in the development of novel therapeutic agents.
Uses
Used in Pharmaceutical Synthesis:
tert-butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate is used as a key reactant for the synthesis of pharmaceuticals, particularly for the development of CNS penetrant CXCR2 antagonists. These antagonists have the potential to treat CNS demyelinating conditions, which are characterized by the loss of the protective myelin sheath surrounding nerve fibers in the central nervous system.
Used in the Treatment of CNS Demyelinating Conditions:
In the pharmaceutical industry, tert-butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate is used as a building block for the creation of novel therapeutic agents that target CXCR2 receptors. By modulating the activity of these receptors, the synthesized compounds can potentially alleviate the symptoms and progression of CNS demyelinating conditions, such as multiple sclerosis.
Used in Drug Development Research:
In addition to its direct application in pharmaceutical synthesis, tert-butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate also serves as a valuable research tool in drug development. Its unique chemical properties and structural features make it an attractive candidate for further exploration and optimization, potentially leading to the discovery of new and more effective treatments for a range of medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1147557-97-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,7,5,5 and 7 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1147557-97:
(9*1)+(8*1)+(7*4)+(6*7)+(5*5)+(4*5)+(3*7)+(2*9)+(1*7)=178
178 % 10 = 8
So 1147557-97-8 is a valid CAS Registry Number.
1147557-97-8Relevant articles and documents
AZASPIROCYCLES AS MONOACYLGLYCEROL LIPASE MODULATORS
-
Page/Page column 71, (2021/10/02)
Azaspirocycle compounds of Formula (I), and pharmaceutically acceptable salts, isotopes, N-oxides, solvates, and stereoisomers thereof, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, such as those associated with pain, psychiatric disorders, neurological disorders (including, but not limited to major depressive disorder, treatment resistant depression, anxious depression, autism spectrum disorders, Asperger syndrome, bipolar disorder), cancers and eye conditions: wherein X, R1, R2a, R2b, R3, m, n, o, and p are defined herein.
6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS
-
Paragraph 0321-0322, (2021/11/13)
The present disclosure provides 6-heteroaryloxy benzimidazole and azabenzimidazole compounds and compositions thereof useful for inhibiting JAK2.
OXADIAZOLES AS AGONISTS OF THE MUSCARINIC M1 AND/OR M4 RECEPTOR
-
Page/Page column 56, (2020/01/11)
This invention relates to compounds that are agonists of the muscarinic M1 and/or M4 receptor and which are useful in the treatment of diseases mediated by the muscarinic M1 and M4 receptors. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula (I) where X1; X2; X3; X4; R1 R2 and R4 are as defined herein.
