114866-05-6

Basic information

• Product Name: 1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(3,4-dimethoxyphenyl)-1,3-propanedione
• Synonyms: 1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(3,4-dimethoxyphenyl)-1,3-propanedione
• CAS NO: 114866-05-6
• Molecular Weight: 390.39
• Mol File: 114866-05-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(3,4-dimethoxyphenyl)-1,3-propanedione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(3,4-dimethoxyphenyl)-1,3-propanedione(114866-05-6)
• EPA Substance Registry System: 1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(3,4-dimethoxyphenyl)-1,3-propanedione(114866-05-6)

Safety Data

• Hazardous Substances Data: 114866-05-6(Hazardous Substances Data)

Upstream product

• 114866-06-7 2'-(3,4-dimethoxybenzoyloxy)-3',4',6'-trimethoxyacetophenone 
• 7507-98-4 1-(2-hydroxy-3,4,6-trimethoxyphenyl)ethanone 
• 3535-37-3 3,4-dimethoxybenzoic acid chloride 

Downstream Products

• 18003-33-3 3',4',5,6,7-pentahydroxyflavone 
• 13003-74-2 5-hydroxy-3’,4’,7,8-tetramethoxyflavone 
• 17290-70-9 isosinensetin 

Relevant articles and documents

Miscrowave-assisted efficient synthesis of polymethoxyacetophenones and natural polymethoxyflavones, and thier inhibitory effects on melanogenesis

Microwave, assisted Friedel-Crafts acetylation of polymethoxybenzenes with acetic anhydride in the presence of In(CF3SO3)3 under solvent-free conditions was achieved rapidly to give polymethoxyacetophenones in high yields. Microwave-assisted benzoylation of 2'-hydroxypolymethoxyacetophenones with polymethoxybenzoyl chlorides, followed by the rearrangement of the resulting benzoates and the final formation of natural polymethoxyflavones was achieved rapidly and efficiently. The polymethoxyflavones showed inhibitory effects on melanogenesis in human melanoma cells.