114884-45-6 Usage
General Description
4'-[(2R)-2-Methylbutyl]-[1,1'-biphenyl]-4-carbonitrile, also known as TCC (triclocarban), is a synthetic organic compound commonly used as an antimicrobial agent in personal care products such as soaps, lotions, and deodorants. It is a white powdered substance that is insoluble in water but soluble in organic solvents. TCC works by inhibiting the growth of bacteria and fungus, making it an effective ingredient in products designed to improve hygiene and prevent the spread of infections. However, TCC has been associated with potential health and environmental concerns, leading to restrictions on its use in some countries. Studies have shown that TCC can accumulate in the environment and potentially disrupt the endocrine system in animals and humans. As a result, some regulatory agencies have restricted or banned the use of TCC in certain personal care products.
Check Digit Verification of cas no
The CAS Registry Mumber 114884-45-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,8,8 and 4 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 114884-45:
(8*1)+(7*1)+(6*4)+(5*8)+(4*8)+(3*4)+(2*4)+(1*5)=136
136 % 10 = 6
So 114884-45-6 is a valid CAS Registry Number.
114884-45-6Relevant articles and documents
An Efficient Asymmetric Synthesis of a Liquid Crystal
Tius, Marcus A.,Gu, Xue-qin,Truesdell, Joel W.,Savariar, Selvaraj,Crooker, P. P.
, p. 36 - 40 (2007/10/02)
A synthesis of L-(-)-4-(2-methylbutyl)phenyl4'-(2-methylbutyl)biphenyl-4-carboxylate (CE2) and of related chiral liquid crystals has been reported; nevertheless, a detailed experimental and spectrometric characterization of both the intermediates and the final product has been lacking in the literature.We present here the first synthesis of the enantiomer of CE2 with full experimental details including spectroscopic data for each of the intermediates.The description of the synthesis of (R)-(+)-2-methylbutanyl will be broadly useful for preparing other liquid crystals with optically active (R)-2-methylbutyl side chains.