1149620-37-0

Basic information

• Product Name: 1H-benzimidazolyl benzyl sulfoxide
• CAS NO: 1149620-37-0
• Molecular Weight: 256.328
• Mol File: 1149620-37-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-benzimidazolyl benzyl sulfoxide(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-benzimidazolyl benzyl sulfoxide(1149620-37-0)
• EPA Substance Registry System: 1H-benzimidazolyl benzyl sulfoxide(1149620-37-0)

Safety Data

• Hazardous Substances Data: 1149620-37-0(Hazardous Substances Data)

Upstream product

• 51290-77-8 2-(benzylthio)-1H-benzo[d]imidazole 

Relevant articles and documents

Catalytic asymmetric oxidation of heteroaromatic sulfides with tert-butyl hydroperoxide catalyzed by a titanium complex with a new chiral 1,2-diphenylethane-1,2-diol ligand

Heteroaromatic sulfoxides, especially 1H-benzimidazolyl pyridinylmethyl sulfoxides, usually used as the blockbuster gastric proton pump inhibitors (PPIs), have been prepared highly enantioselectivily by catalytic asymmetric oxidation of sulfides attached to nitrogen-containing heterocyles with tert-butyl hydroperoxide in the presence of a chiral titanium complex, formed in situ from Ti(iPrO)4, chiral 1,2-diphenylethane-1,2-diol 3c and water. The chiral sufoxides were obtained in high yield (97%) with excellent enantiomeric excess (up to 98%).