1150-90-9

Basic information

• Product Name: Estratetraenol
• Synonyms: Estra-1,3,5(10),16-Tetraen-3-Ol;Estratetraenol;(8S,9S,13S,14S)-13-methyl-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]ph enanthren-3-ol;1,3,5(10),16-Estratetren-3-ol;1,3,5(10),16-Estratetraen-3-ol;(8S,9S,13R,14S)-13-methyl-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-ol;CoMpound 742;ESTRA-1,3-5(10),16-TERAEN-3-OL
• CAS NO: 1150-90-9
• Molecular Formula: C₁₈H₂₂O
• Molecular Weight: 254.37
• Product Categories: Steroids
• Mol File: 1150-90-9.mol
• Article Data: 12

Chemical Properties

• Melting Point: 130-131.5 °C
• Boiling Point: 400.2 °C at 760mmHg
• Flash Point: 180.6 °C
• Appearance: /
• Density: 1.111 g/cm³
• Vapor Pressure: 5.59E-07mmHg at 25°C
• Refractive Index: 1.592
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• PKA: 14.03±0.40(Predicted)
• CAS DataBase Reference: Estratetraenol(CAS DataBase Reference)
• NIST Chemistry Reference: Estratetraenol(1150-90-9)
• EPA Substance Registry System: Estratetraenol(1150-90-9)

Safety Data

• Hazardous Substances Data: 1150-90-9(Hazardous Substances Data)

Usage

Description

Estratetraenol, also known as a 3-hydroxy steroid, is a chemical compound obtained by formal dehydration at the 17-position of estradiol. It is a yellow solid with pheromone activities, primarily produced by females. Its unique chemical properties and biological functions make it a versatile compound with various applications across different industries.

Uses

Used in Pharmaceutical Industry:
Estratetraenol is used as a pharmaceutical agent for its hormone-like effects and potential applications in treating various health conditions related to hormone imbalances. Its ability to mimic the actions of estrogen makes it a valuable compound for research and development in the pharmaceutical sector.
Used in Cosmetics Industry:
In the cosmetics industry, Estratetraenol is used as an ingredient in various skincare and beauty products due to its hormone-like properties. It is believed to help with skin rejuvenation, reducing the signs of aging, and maintaining overall skin health.
Used in Research and Development:
Estratetraenol is used as a research compound for studying the effects of hormones on the human body. Its pheromone activities make it an interesting subject for research in the fields of biology, endocrinology, and neuroscience.
Used in Agriculture:
Estratetraenol can be used in the agricultural industry as a pheromone to control pest populations. Its ability to attract or repel certain insects can be harnessed to develop more targeted and environmentally friendly pest control strategies.
Used in Environmental Science:
In environmental science, Estratetraenol can be used to study the effects of hormones on wildlife and ecosystems. Understanding how these compounds interact with the environment can help in developing strategies to mitigate the impact of hormonal pollutants on wildlife and their habitats.

InChI:InChI=1/C18H22O/c1-18-9-2-3-17(18)16-6-4-12-11-13(19)5-7-14(12)15(16)8-10-18/h2,5,7,9,11,15-17,19H,3-4,6,8,10H2,1H3/t15-,16-,17+,18+/m1/s1

Upstream product

• 50-28-2 estradiol 
• 53-16-7 Estrone 
• 55105-93-6 estrone p-toluenesulfonylhydrazone 
• 23880-57-1 (8S,9S,13R,14S)-3-(benzyloxy)-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthrene 

Downstream Products

• 1316291-21-0 (8R,9S,13S,14S)-3-(benzyloxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-16,17-diol 
• 23880-57-1 (8S,9S,13R,14S)-3-(benzyloxy)-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthrene 
• 472-56-0 Estroxide 

Relevant articles and documents

A pharmaceutical composition containing 2-hydroxy-7-methyl octahydrophenanthrene derivative as an estrogen receptor ligand or a pharmaceutically acceptable salt thereof as an effective component

Provided are a compound represented by chemical formulas I and II, or a pharmaceutically acceptable ester, amide, or carbamate salt thereof; and a solvent compound comprising a solvent compound of the ester, amide, or carbamate salt thereof. In addition, provided are use of the compound in treating or preventing diseases or disorders related to activation of an estrogen receptor, and a pharmaceutical composition comprising the compound. In chemical formulas I and II, definitions of R_1, R_2, R_3, and R_4 are the same as those in the specification.COPYRIGHT KIPO 2016

Androstane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods

The invention relates to a method of altering hypothalamic function in an individual. The method comprises nasally administering a human semiochemical, e.g. an Androstane steroid, or a pharmaceutical composition containing a semiochemical, such that the ligand semiochemical binds to a specific neuroepithelial receptor. The steroid or steroids is/are preferably administered in the form of a pharmaceutical composition containing one or more pharmaceutically acceptable carriers. Other embodiments of the invention include pharmaceutical compositions containing the steroids.

Steroids as neurochemical stimulators of the VNO to alleviate pain

The invention relates to a method of alleviating pain. The method comprises nasally administering a steroid which is a human vomeropherin, such that the vomeropherin binds to a specific neuroepithelial receptor. The steroid or steroids is/are preferably administered in the form of a pharmaceutical composition containing one or more pharmaceutically acceptable carriers.