115054-62-1Relevant articles and documents
Renal-selective prodrugs for control of renal sympathetic nerve activity in the treatment of hypertension
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Page/Page column 66-67, (2010/11/30)
Renal-selective prodrugs are described which are preferentially converted in the kidney to compounds capable of inhibiting synthesis of catecholamine-type neurotransmitters involved in renal sympathetic nerve activity. The prodrugs described herein are de
A facile method for the side-chain protection of α-methyl-β-3,4-dihydroxyphenyl-L-alanine (αMeDopa) for solid-phase peptide synthesis
Hsieh,deMaine
, p. 59 - 62 (2007/10/02)
Two approaches have been used to prepare N(α)-tert-butoxycarbonyl-α-methyl-β-3,4-dimethoxy-, or dibenzyloxyphenyl-L-alanine, N(α)-Boc-α-MeDopa(R)2, where R is the methyl or benzyl ether. In the first approach, α-methyl-β-3,4-dihydroxyphenyl-L-a