115126-97-1

Basic information

• Product Name: Benzoic acid, 3,5-bis(1,1-dimethylethyl)-4-methoxy-, methyl ester
• CAS NO: 115126-97-1
• Molecular Formula: C17H26O3
• Molecular Weight: 278.392
• Mol File: 115126-97-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 3,5-bis(1,1-dimethylethyl)-4-methoxy-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3,5-bis(1,1-dimethylethyl)-4-methoxy-, methyl ester(115126-97-1)
• EPA Substance Registry System: Benzoic acid, 3,5-bis(1,1-dimethylethyl)-4-methoxy-, methyl ester(115126-97-1)

Safety Data

• Hazardous Substances Data: 115126-97-1(Hazardous Substances Data)

Upstream product

• 1421-49-4 3,5-Di-tert-butyl-4-hydroxybenzoic acid 
• 74-88-4 methyl iodide 
• 2511-22-0 methyl 3,5-di-tert-butyl-4-hydroxybenzoate 
• 115126-96-0 3,5-Di-tert-butyl-4-(chloro-diphenyl-silanyloxy)-benzoic acid methyl ester 

Downstream Products

• 93156-92-4 3,5-Bis(1,1-dimethylethyl)-4-methoxy-benzoic acid 

Relevant articles and documents

CYCLYLAMINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS

Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type and/or T-type calcium channel activity are disclosed. Specifically, a series of compounds of substituted or unsubstituted cyclylamine derivatives as shown in formulas (1).

Calcium channel inhibitors comprising benzhydril spaced from piperazine

Certain piperazine substituted compounds are described which are useful in altering calcium channel activity.

NUCLEOPHILIC SUBSTITUTION AT SILICON: SYNTHESIS OF STERICALLY-HINDERED BIS(2,6-DI-t-BUTYLARYLOXY)SILANES

The reaction of the monomethylsilane (8a) with two equivalents of the 4-carboalkoxy)-2,6-di-t-butyl-substituted phenol (7b) in toluene using triethylamine as an acid acceptor gave the bis(aryloxy) adduct (9a).The analogous reaction of the dimethylsilane (8b) with sodium 2,6-di-t-butyl-4-(methoxycarboxyl)-phenolate (7a) gave only the monosubstitution product (10a).The raction of the corresponding phenolate (7e) with 8b gave a mixture of 7a, 10a, and bis-adduct (9b), whereas, in the presence of 15-crown-5, the bis adduct 9b was obtained.The bis-adducts 9c-e were prepared in an analogous manner.The reaction of n-hexyl 3,5-di-t-butyl-4-hydroxylbenzoate (7h) with the diphenylsilane (8c) gave only the monosubstitution product 12, while forcing conditions gave, unexpectedly, the methyl ether 13.The reaction of 4-(carboalkoxyethyl)-2,6-di-t-butylphenol (16a) with 8a gave the bis adduct.The reaction af 16a with 8b in THF, without a crown ether, gave a low yield of the monosubstitution product.The bis-adducts 17b-c were obtained by the reaction of 8b with the corresponding phenolates (16a-b) in tetraglyme.Compound 17b was also obtained by the reaction of 8b with 16a in THF with a crown ether.These results are discussed in terms of charge dispersal in the phenolate ion and the corresponding effect upon both ion-pairing and aggregation in solution.