115135-38-1 Usage
Description
3-Hydroxy-3-Methylglutaric-d3 Anhydride is an organic compound that belongs to the class of 3-alkyl-3-hydroxyglutaric acids. It is characterized by its off-white solid appearance and is known for its hypocholesterolemic properties, acting as a potent inhibitor of HMG CoA reductase.
Uses
Used in Pharmaceutical Industry:
3-Hydroxy-3-Methylglutaric-d3 Anhydride is used as a hypocholesterolemic agent for the treatment of high cholesterol levels. It functions by inhibiting the enzyme HMG CoA reductase, which plays a crucial role in the biosynthesis of cholesterol in the body. This inhibition helps to lower the levels of low-density lipoprotein (LDL) cholesterol, thereby reducing the risk of cardiovascular diseases.
Additionally, due to its unique chemical structure, 3-Hydroxy-3-Methylglutaric-d3 Anhydride may also be utilized in the development of new drugs targeting various other medical conditions, making it a valuable compound in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 115135-38-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,1,3 and 5 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 115135-38:
(8*1)+(7*1)+(6*5)+(5*1)+(4*3)+(3*5)+(2*3)+(1*8)=91
91 % 10 = 1
So 115135-38-1 is a valid CAS Registry Number.
115135-38-1Relevant articles and documents
Ring D Expansion and Aromatisation in the Biosynthesis of Nic-1, an Antifeedant Steroid from Nicandra physaloides
Gill, Harjit K.,Smith, Roland W.,Whiting, Donald A.
, p. 2989 - 2993 (2007/10/02)
Isotope administration experiments with Nicandra physaloides plants using 2H3>- and 14C3>-mevalonic acid, analysed by 2H NMR and by degradation, respectively, show that the aromatic ring-D of Nic-1 (2) is formed by ring-D expansion in a steroid precursor with oxidative inclusion of the C/D angular methyl.