115142-05-7

Basic information

• Product Name: uridine 3'-(2,5-dichlorophenyl) phosphate
• Synonyms: uridine 3'-(2,5-dichlorophenyl) phosphate
• CAS NO: 115142-05-7
• Molecular Weight: 469.172
• Mol File: 115142-05-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: uridine 3'-(2,5-dichlorophenyl) phosphate(CAS DataBase Reference)
• NIST Chemistry Reference: uridine 3'-(2,5-dichlorophenyl) phosphate(115142-05-7)
• EPA Substance Registry System: uridine 3'-(2,5-dichlorophenyl) phosphate(115142-05-7)

Safety Data

• Hazardous Substances Data: 115142-05-7(Hazardous Substances Data)

Upstream product

• 34198-35-1 2',5'-di-O-tetrahydropyran-2-yluridine 
• 53676-18-9 2,5-dichlorophenyl phosphorodichloridate 
• 34304-58-0 5'-O-(4-monomethoxytrityl)-2'-O-(tetrahydropyran-2-yl)uridine 
• 115142-17-1 Phosphoric acid 2,5-dichloro-phenyl ester (2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-(tetrahydro-pyran-2-yloxy)-2-(tetrahydro-pyran-2-yloxymethyl)-tetrahydro-furan-3-yl ester 

Downstream Products

• 54976-92-0 2,5-dichlorophenate 
• 84-53-7 uridine-3'-phosphate 
• 583-78-8 2,5-dichlorophenol 
• 606-02-0 uridine 2',3'-cyclic phosphate 

Relevant articles and documents

The mechanism of the metal ion promoted cleavage of RNa phosphodiester bonds involves a general acid catalysis by the metal aquo ion on the departure of the leaving group

A series of uridine 3′-alkyl phosphates and 3′-aryl phosphates were synthesised and their cleavage was studied in the presence of Zn2+ aquo ions. A βlg value was determined for the Zn2+ promoted cleavage of both types of compounds. Comparison of the results obtained to those reported previously for the cleavage of the same substrates in the absence of metal ion catalysts suggests that the alkyl leaving group departs as an alcohol in the presence of metal ion catalysts. Furthermore, metal ion catalysts seem to enhance the departure. The aryl leaving group, in contrast, departs as an oxyanion.