115147-85-8

Basic information

• Product Name: 4-aza-3-benzyloxy-3-phenyl-1(3H)-isobenzofuranone 4-oxide
• CAS NO: 115147-85-8
• Molecular Weight: 347.327
• Mol File: 115147-85-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-aza-3-benzyloxy-3-phenyl-1(3H)-isobenzofuranone 4-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-aza-3-benzyloxy-3-phenyl-1(3H)-isobenzofuranone 4-oxide(115147-85-8)
• EPA Substance Registry System: 4-aza-3-benzyloxy-3-phenyl-1(3H)-isobenzofuranone 4-oxide(115147-85-8)

Safety Data

• Hazardous Substances Data: 115147-85-8(Hazardous Substances Data)

Upstream product

• 2398-81-4 Nicotinic acid N-oxide 
• 93-97-0 benzoic acid anhydride 

Downstream Products

• 115147-86-9 2-benzoylnicotinic acid 1-oxide 

Relevant articles and documents

Reactions of Nicotinic Acid 1-Oxide with Propionic, Phenylacetic and Benzoic Anhydrides

Nicotinic acid 1-oxide (1) reacts with hot propionic anhydride to give 4-aza-3-ethyl-3-propionyloxy-1(3H)-isobenzofuranone 4-oxide (2), 5-aza-3-methyl-4-propionyloxyisocoumarin (3), 4-aza-3-ethyl-3-propionyloxy-1(3H)-isobenzofuranone (4), 4-aza-3-ethyl-3,5-dipropionyloxy-1(3H)-isobenzofuranone (5) and a mixture of 2- and 6-hydroxynicotinic acids (6 and 7).Product 2 is a 2-propionylation product of 1, and 3, 4 and 5 arise from further action of the anhydride on 2.Phenylacetic anhydride undergoes oxidative decarboxylation with 1 to give benzaldehyde and nicotinic acid.The reaction of 1 with benzoic anhydride affords a 2-benzoylation product 4-aza-3-benzoyloxy-3-phenyl-1(3H)-isobenzofuranone 4-oxide (12).Keywords - nicotinic acid 1-oxide; 4-aza-1(3H)-isobenzofuranone 4-oxide; 5-azaisocoumarin; propionic anhydride; phenylacetic anhydride; benzoic anhydride; 2-propionylation; 2-benzoylation; deoxygenative β-propionyloxylation; oxidative decarboxylation