1151890-36-6Relevant articles and documents
Effects of crystal form on solubility and pharmacokinetics: A crystal engineering case study of lamotrigine
Cheney, Miranda L.,Shan, Ning,Healey, Elisabeth R.,Hanna, Mazen,Wojtas, Lukasz,Zaworotko, Michael J.,Sava, Vasyl,Song, Shijie,Sanchez-Ramos, Juan R.
, p. 394 - 405 (2010)
In this contribution, we describe how the supramolecular synthon approach, can be used for discovery of novel crystal forms and for enhancing the relevant preclinical properties of a low solubility antiepileptic drug, lamotrigine (6-(2,3dichlorophenyl)-l,