1152617-99-6Relevant articles and documents
RADIOLABELLED mGluR2 PET LIGANDS
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, (2013/09/12)
The present invention relates to novel, selective, radiolabelled mGluR2 ligands which are useful for imaging and quantifying the metabotropic glutamate receptor mGluR2 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo and to precursors of said compounds.
Discovery and pharmacological characterization of aryl piperazine and piperidine ethers as dual acting norepinephrine reuptake inhibitors and 5-HT1A partial agonists
Gray, David L.,Xu, Wenjian,Campbell, Brian M.,Dounay, Amy B.,Barta, Nancy,Boroski, Susan,Denny, Lynne,Evans, Lori,Stratman, Nancy,Probert, Al
scheme or table, p. 6604 - 6607 (2010/06/12)
Compounds that are both norepinephrine reuptake inhibitors (NRI) and 5-HT1A partial agonists may have the potential to treat neuropsychiatric disorders including attention deficit hyperactivity disorder (ADHD) and depression. Targeted screening