115298-62-9

Basic information

• Product Name: 2-Naphthalenecarboxylic acid, 1,1-dimethylethyl ester
• CAS NO: 115298-62-9
• Molecular Formula: C15H16O2
• Molecular Weight: 228.291
• Mol File: 115298-62-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Naphthalenecarboxylic acid, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Naphthalenecarboxylic acid, 1,1-dimethylethyl ester(115298-62-9)
• EPA Substance Registry System: 2-Naphthalenecarboxylic acid, 1,1-dimethylethyl ester(115298-62-9)

Safety Data

• Hazardous Substances Data: 115298-62-9(Hazardous Substances Data)

Upstream product

• 2459-25-8 methyl naphthalene-2-carboxylate 
• 865-47-4 potassium tert-butylate 

Downstream Products

• 1088150-22-4 (2,5-dimethylphenyl)naphthalen-2-ylmethanone 
• 2243-83-6 2-naphthaloyl chloride 
• 91-57-6 2-Methylnaphthalene 

Relevant articles and documents

Ruthenium-catalyzed ester reductions applied to pharmaceutical intermediates

Ruthenium pincer complexes were synthesized and used for catalytic ester reductions under mild conditions (～5 bar of hydrogen). An experimental design approach was used to optimize the conditions for yield, purity, and robustness. Evidence for the catalytically active ruthenium dihydride species is presented. Observed intermediates and side products, as well as time-course data, were used to build mechanistic insight. The optimized procedure was further demonstrated through scaled-up reductions of two pharmaceutically relevant esters, both in batch and continuous flow.