1153421-34-1

Basic information

• Product Name: methyl 2-((methoxycarbonyl)amino)-5-methylbenzoate
• Synonyms: methyl 2-((methoxycarbonyl)amino)-5-methylbenzoate
• CAS NO: 1153421-34-1
• Molecular Weight: 223.229
• Mol File: 1153421-34-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: methyl 2-((methoxycarbonyl)amino)-5-methylbenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-((methoxycarbonyl)amino)-5-methylbenzoate(1153421-34-1)
• EPA Substance Registry System: methyl 2-((methoxycarbonyl)amino)-5-methylbenzoate(1153421-34-1)

Safety Data

• Hazardous Substances Data: 1153421-34-1(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 608-05-9 5-methyl-indole-2,3-dione 
• 614-96-0 5-methyl-1H-indole 
• 40314-06-5 5-methyl-1H-isoindole-1,3-(2H)-dione 

Relevant articles and documents

An Electrochemical Route for Special Oxidative Ring-Opening of Indoles

A novel electrochemical protocol for the oxidative cleavage of indoles has been developed, which o?ers a simple way to access synthetically useful anthranilic acid derivatives. In undivided cells, a wide variety of indoles and alcohol compounds are examined to a?ord amide ester aromatics without using extra oxidants and stoichiometric metal catalysts, which avoids the formation of undesired by-products and exhibits high atom economy. The products we described in this perspective represent a synthetic intermediate in numerous drug molecules and industrial chemical reagents and remarkably show potential application in the future.

Oxidative Cleavage of C2-C3 Bond in Isatin Using (Diacetoxyiodo)benzene: A Facile Synthesis of Carbamates of Alkyl Anthranilates

On reaction with (diacetoxyiodo)benzene, isatin and N-acetyl isatin undergo the oxidative C2-C3 bond cleavage to form carbamates of alkyl anthranilates and alkyl 2-acetamidobenzoate, respectively.

Hofmann-type rearrangement of imides by in situ generation of imide-hypervalent iodines(III) from iodoarenes

The Hofmann-type rearrangement of aromatic and aliphatic imides using a hypervalent iodine(III) reagent generated in situ from PhI, m-CPBA, and TsOH·H2O proceeded in the presence of a base in alcohol to provide anthranilic acid derivatives and amino acid derivatives in high yields, respectively. This reaction proceeds through a tandem reaction via alcoholysis followed by a Hofmann rearrangement promoted by the formation of an imide-λ3-iodane intermediate.