1154-46-7

Basic information

• Product Name: 2H-Isoindole-2-heptanoic acid, 1,3-dihydro-1,3-dioxo-
• CAS NO: 1154-46-7
• Molecular Formula: C15H17NO4
• Molecular Weight: 275.304
• Mol File: 1154-46-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2H-Isoindole-2-heptanoic acid, 1,3-dihydro-1,3-dioxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Isoindole-2-heptanoic acid, 1,3-dihydro-1,3-dioxo-(1154-46-7)
• EPA Substance Registry System: 2H-Isoindole-2-heptanoic acid, 1,3-dihydro-1,3-dioxo-(1154-46-7)

Safety Data

• Hazardous Substances Data: 1154-46-7(Hazardous Substances Data)

Upstream product

• 85-44-9 phthalic anhydride 
• 929-17-9 7-aminoheptanoic acid 

Downstream Products

• 138349-42-5 3-methyl-1-phenyl-2-(7-phthalimidoheptanoyl)aminoindole 
• 138349-47-0 7-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-heptanoic acid (3-ethyl-1-phenyl-1H-indol-2-yl)-amide 
• 138349-48-1 7-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-heptanoic acid (3-isopropyl-1-phenyl-1H-indol-2-yl)-amide 
• 138349-45-8 7-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-heptanoic acid [3-methyl-1-(4-nitro-phenyl)-1H-indol-2-yl]-amide 
• 138349-43-6 7-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-heptanoic acid [5-methoxy-3-methyl-1-(4-nitro-phenyl)-1H-indol-2-yl]-amide 
• 102952-16-9 2-(4-dimethylamino-phenylimino)-3-oxo-9-phthalimido-nonanenitrile 
• 103033-63-2 2-(4-diethylamino-phenylimino)-3-oxo-9-phthalimido-nonanenitrile 

Relevant articles and documents

Synthesis and antiherpetic activity of novel purine conjugates with 7,8-difluoro-3-methyl-3,4-dihydro-2H-1,4-benzoxazine

[Figure not available: see fulltext.] A method for the synthesis of novel purine conjugates with 7,8-difluoro-3-methyl-3,4-dihydro-2H-1,4-benzoxazine containing fragments of ω-amino acids with different lengths of the polymethylene chain as a linker has been developed. It was found in experiments in vitro that the obtained compounds are active against the herpes simplex virus type 1, including the acyclovir-resistant strain.

GUANIDINO IMIDAZOLES AND THIAZOLES

The invention relates to guanidine derivatives of imidazoles and thiazoles which are histamine H-2 antagonists and which inhibit the secretion of gastric acid, to methods for their manufacture, to pharmaceutical compositions containing them and to methods of using such guanidine derivatives and compositions. The guanidine derivatives are of the general formula I: STR1 in which X is S or NH, Y is CH 2, a direct bond or a vinylene radical, m is 0 to 4 and n is 1 to 4, R 1 is hydrogen, halogen or alkyl, R 2 is hydrogen, alkyl, alkanoyl or aroyl, A is a 3,4-dioxocyclobuten-1,2-diyl radical or C=Z in which Z is O, S, NCN, NNO 2, CHNO 2, NCONH 2, C(CN) 2, NCOR 3, NCO 2 R 3, NSO 2 R 3 or NR 4 in which R 3 is alkyl or aryl and R 4 is hydrogen or alkyl, B is alkoxy or alkylthio or NR 5 R 6 in which R 5 and R 6 are independently hydrogen, alkyl, alkenyl, cycloalkyl, hydroxyalkyl, alkoxyalkyl, alkylaminoalkyl or dialkylaminoalkyl; and the salts thereof.