1154063-25-8

Basic information

• Product Name: dimethyl (4-methylphenyl)(4-methylphenylsulfonamido)methylphosphonate
• Synonyms: dimethyl (4-methylphenyl)(4-methylphenylsulfonamido)methylphosphonate
• CAS NO: 1154063-25-8
• Molecular Weight: 383.405
• Mol File: 1154063-25-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: dimethyl (4-methylphenyl)(4-methylphenylsulfonamido)methylphosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl (4-methylphenyl)(4-methylphenylsulfonamido)methylphosphonate(1154063-25-8)
• EPA Substance Registry System: dimethyl (4-methylphenyl)(4-methylphenylsulfonamido)methylphosphonate(1154063-25-8)

Safety Data

• Hazardous Substances Data: 1154063-25-8(Hazardous Substances Data)

Upstream product

• 36198-87-5 dimethyl trimethylsilyl phosphite 
• 75159-10-3 N-(4-methylbenzylidene)-p-toluenesulfonamide 
• 868-85-9 Dimethyl phosphite 
• 70-55-3 toluene-4-sulfonamide 
• 96-36-6 methyl phosphite 
• 104-87-0 4-methyl-benzaldehyde 

Relevant articles and documents

Enantioselective Aza-Reformatsky Reaction with Ketimines

Here, an enantioselective aza-Reformatsky reaction using acyclic ketimine substrates is presented. Using α-phosphorated ketimines as electrophilic substrates and a simple BINOL-derived ligand, phosphorated analogues of aspartic acid holding chiral tetrasubstituted carbons are efficiently obtained with excellent enantioselectivity through an asymmetric organocatalytic Reformatsky-type reaction. The phosphorated analogues of aspartic acid have been used for the synthesis of phosphorus-containing enantiopure tetrasubstituted β-lactams.

Hydrophosphonylation of aldimines under catalysts-free conditions

Trimethylsilyl phosphite reacted with aldimines efficiently under catalysts-free conditions, giving α-aminophosphonates in good to excellent yields. Furthermore, the reaction can be scaled-up easily and the high yield can be maintained. Copyright

Iodine-catalyzed efficient hydrophosphonylation of N-tosyl aldimines

(Chemical Equation Presented) Treatment of N-tosyl aldimines with dialkyl trimethylsilyl phosphites at 0°C in the presence of iodine as a catalyst afforded the corresponding sulfonamide phosphonates in excellent yields within 1.5 to 2.5 h.