115483-29-9

Basic information

• Product Name: Benzene, 5-azido-1,2,3-trimethoxy-
• CAS NO: 115483-29-9
• Molecular Formula: C9H11N3O3
• Molecular Weight: 209.205
• Mol File: 115483-29-9.mol
• Article Data: 40

Chemical Properties

• CAS DataBase Reference: Benzene, 5-azido-1,2,3-trimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 5-azido-1,2,3-trimethoxy-(115483-29-9)
• EPA Substance Registry System: Benzene, 5-azido-1,2,3-trimethoxy-(115483-29-9)

Safety Data

• Hazardous Substances Data: 115483-29-9(Hazardous Substances Data)

Upstream product

• 182163-96-8 3,4,5-trimethoxyphenylboronic Acid 
• 24313-88-0 3,4,5-Trimethoxyaniline 
• 634-36-6 1,2,3-trimethoxybenzene 
• 214360-67-5 4,4,5,5-tetramethyl-2-(3,4,5-trimethoxyphenyl)-1,3,2-dioxaborolane 

Downstream Products

• 24313-88-0 3,4,5-Trimethoxyaniline 
• 1007090-65-4 N-(3,4,5-trimethoxyphenyl)-2-phenylaziridine 
• 1007090-66-5 N-(3,4,5-trimethoxyphenyl)-2-methyl-2-phenylaziridine 
• 1034292-94-8 4-(4-methoxy-3-nitrophenyl)-1-(3,4,5-trimethoxyphenyl)-1H-1,2,3-triazole 
• 1285718-36-6 C₂₅H₂₅N₃O₁₀ 

Relevant articles and documents

Synthesis and biological evaluation of novel 3-O-tethered triazoles of diosgenin as potent antiproliferative agents

Diosgenin, a promising anticancer steroidal sapogenin, was isolated from Dioscorea deltoidea. Keeping its stereochemistry rich architecture intact, a scheme for the synthesis of novel diosgenin analogues was designed using Cu (I)-catalysed alkyne-azide cy

Synthetic modification of hydroxychavicol by Mannich reaction and alkyne-azide cycloaddition derivatives depicting cytotoxic potential

Here we report the design, synthesis and lead optimization of hydroxychavicol (1) a high yielding metabolite ubiquitously present in the Piper betel leaves with the significant cytotoxic activity. This is the first report to describe the synthetic strateg

Synthesis of 3,4,5-trimethoxybenzene derivatives with substituted triazole group by Huisgen 1,3-cycloaddition and their inhibitory effects on 3T3-L1 adipocyte differentiation

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Synthesis and antitumor activity of 1-substituted 1,2,3-triazole-mollugin derivatives

A new series of mollugin-1,2,3-triazole derivatives were synthesized using a copper(I)-catalyzed Huisgen 1,3-dipolar cycloaddition reaction of corresponding O-propargylated mollugin with aryl azides. All the compounds were evaluated for their cytotoxicity on five human cancer cell lines (HL-60, A549, SMMC-7721, SW480, and MCF-7) using MTS assays. Among the synthesized series, most of them showed cytotoxicity and most of all, compounds 14 and 17 exhibited significant cytotoxicity of all five cancer cell lines.

Regioselective synthesis of 4-fluoro-1,5-disubstituted-1,2,3-triazoles from synthetic surrogates of α-fluoroalkynes

α-Fluoroalkynes are elusive molecules due to their instability and inaccessibility. Here, we show that α-fluoronitroalkenes can serve as synthetic surrogates of α-fluoroalkynes in [3+2] cycloaddition reactions with organic azides facilitated by a catalytic amount of trifluoroacetic acid (TFA). This work provides the first regioselective method to access 4-fluoro-1,5-disubstituted-1,2,3-triazoles.