115533-97-6Relevant articles and documents
Gold-catalyzed double migration-benzannulation cascade toward naphthalenes
Dudnik, Alexander S.,Schwier, Todd,Gevorgyan, Vladimir
supporting information; experimental part, p. 1465 - 1468 (2009/04/10)
(Chemical Equation Presented) A novel gold(I)-catalyzed cycloisomerization of propargylic esters leading to unsymmetrically substituted naphthalenes has been developed. This cascade reaction involves an unprecedented tandem sequence of 1,3- and 1,2-migration of two different migrating groups. It is believed that this transformation likely proceeds via the formation of 1,3-diene intermediate or its precursor, which upon cyclization and aromatization steps transforms into the naphthalene core. 2008 American Chemical Society.