1157-63-7

Basic information

• Product Name: 4(1H)-Quinazolinone, 6-methoxy-2-(4-methoxyphenyl)-
• CAS NO: 1157-63-7
• Molecular Formula: C16H14N2O3
• Molecular Weight: 282.299
• Mol File: 1157-63-7.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 4(1H)-Quinazolinone, 6-methoxy-2-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Quinazolinone, 6-methoxy-2-(4-methoxyphenyl)-(1157-63-7)
• EPA Substance Registry System: 4(1H)-Quinazolinone, 6-methoxy-2-(4-methoxyphenyl)-(1157-63-7)

Safety Data

• Hazardous Substances Data: 1157-63-7(Hazardous Substances Data)

Upstream product

• 1882-71-9 2-amino-5-methoxybenzamide 
• 100-07-2 4-methoxy-benzoyl chloride 
• 6298-96-0 1-(4-methoxyphenyl)ethanamine 
• 99848-43-8 2-bromo-5-methoxybenzamide 
• 102-09-0 bis(phenyl) carbonate 
• 138240-22-9 N-(4-methoxyphenyl) 4-methoxybenzamidine 
• 3878-46-4 ethyl phenyl carbonate 
• 104-94-9 4-methoxy-aniline 
• 874-90-8 4-methoxybenzonitrile 
• 123-11-5 4-methoxy-benzaldehyde 
• 105-13-5 4-Methoxybenzyl alcohol 
• 2881-83-6 ethyl 4-methoxybenzoylacetate 
• 201230-82-2 carbon monoxide 
• 696-62-8 para-iodoanisole 

Downstream Products

• 911469-36-8 4-(6-acetoxy-4-oxo-3,4-dihydroquinazolin-2-yl)phenyl acetate 

Relevant articles and documents

Br?nsted acid catalyzed synthesis of 2‐aryl‐quinazolinones via cyclization of 2‐aminobenzamide with benzonitriles in PEG

A simple and efficient Br?nsted acid catalyzed synthesis of 2‐aryl‐quinazolinones via cyclization of 2‐aminobenzamides with benzonitrile in PEG under metal and ligand‐free condition. All substituted benzonitriles were also well participated with the formation of the corresponding products in moderate to good yields.

Method for synthesizing quinazolinone compound by photo-catalyzing alcohol oxidation in water phase

The invention discloses a method for synthesizing a quinazolinone compound by photo-catalyzing alcohol oxidation in a water phase, which comprises the following steps: by taking a compound shown as aformula (I) and a compound shown as a formula (II) as raw materials and water as a solvent, adding a visible light catalyst, and reacting under the conditions of alkali and visible light to obtain a quinazolinone compound (III). The method for preparing the quinazolinone compound is environmentally friendly, easy and convenient to operate, safe, cheap and efficient. Compared with the prior art, the method is applicable to a large number of functional groups, high in yield, few in byproducts, simple and safe to operate, low in cost and environment-friendly; wherein R1 is H, C1-C4 alkoxy, halogen or nitro; and R2 is H, substituted or unsubstituted phenyl, 2-pyridyl, 2-thienyl or 5-methylfuryl.

Efficient and selective microwave-assisted copper-catalyzed synthesis of quinazolinone derivatives in aqueous

Microwave-assisted copper-catalyzed cascade reactions between 2-halobenzoic acids and amidines to synthesize quinazolinone derivatives in water are reported. A variety of target products were obtained in good to excellent yields up to 94%. Its application was performed by the synthesis of 4-(1H-benzo[d]imidazol-2-ylthio)-6-methoxypteridine, which displayed significant anti-proliferation effect.