1157884-58-6 Usage
Description
((2R,3R,4S)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methylbenzoate is a tetrahydrofuran derivative featuring a benzoyloxy group at the 3-position and a methylbenzoate group at the 2-position. ((2R,3R,4S)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methylbenzoate also incorporates a fluorine atom at the 4-position and a ketone group at the 5-position, endowing it with unique structural properties that may confer biological activity. Its fluorine atom and functional groups could enhance its utility in both pharmaceutical development and organic synthesis, particularly as a chiral building block. Furthermore, the presence of benzoyloxy and methylbenzoate groups may improve the compound's solubility and stability across different solvents.
Uses
Used in Pharmaceutical Development:
((2R,3R,4S)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methylbenzoate is used as a potential pharmaceutical agent due to its unique structure that may exhibit biological activity. The presence of the fluorine atom could provide specific binding affinities or metabolic properties, making it a candidate for the development of new drugs.
Used in Organic Synthesis:
In the field of organic synthesis, ((2R,3R,4S)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methylbenzoate serves as a chiral building block. Its distinct stereochemistry and functional groups can be leveraged to construct more complex molecules with desired properties, which is valuable in creating enantioselective synthetic pathways.
Used in Solvent Systems:
((2R,3R,4S)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methylbenzoate is used to improve solubility and stability in various solvents owing to the presence of benzoyloxy and methylbenzoate groups. This makes it a useful compound in formulations where maintaining solubility and stability is critical for the compound's performance or shelf life.
Check Digit Verification of cas no
The CAS Registry Mumber 1157884-58-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,7,8,8 and 4 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1157884-58:
(9*1)+(8*1)+(7*5)+(6*7)+(5*8)+(4*8)+(3*4)+(2*5)+(1*8)=196
196 % 10 = 6
So 1157884-58-6 is a valid CAS Registry Number.
1157884-58-6Relevant articles and documents
Preparation method of fluorodesoxyribofuranose
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Page/Page column 0126; 0127, (2016/10/09)
The invention provides a preparation method of fluorodesoxyribofuranose. The structure of the fluorodesoxyribofuranose is represented by general formula 1 shown in the description; and the general formula 1, 1a:R = F, and R' = Me; and 1b:R = Me, and R' = F. The fluorodesoxyribofuranose prepared through the brand new preparation method can be used in researching of new medicines, or can be used in researches as a research model. The method adopts glyceraldehyde acetonide as a raw material and allows enantiomers in all intermediates to be effectively separated through a four-step reaction by adopting a rectification or distillation and re-crystallization technology, and a 2-posiion single optical isomer in the target product is directly constructed through an enol addition reaction, so the preparation of the target compound is smooth completed, and the method has the advantages of high yield, simple operation, and suitableness for promotion and application.
A neighboring group participation strategy: Facile synthesis of 3,5-di-O-benzoyl-2-C-methyl-d-arabino-γ-lactone
Xie, Yuanchao,Zhang, Jian,Tian, Guanghui,Xu, Mingshuo,Hu, Tianwen,Jiang, Xiangrui,Shen, Jingshan
, p. 4345 - 4348 (2015/06/22)
A simple and efficient approach for the synthesis of 3,5-di-O-benzoyl-2-C-methyl-d-arabino-γ-lactone through a neighboring group participation mechanism is reported. This compound could be a useful precursor for the synthesis of nucleoside antiviral agents.
