115819-23-3

Basic information

• Product Name: (E)-2,5-dimethyl-2,5-heptadien-4-one
• Synonyms: (E)-2,5-dimethyl-2,5-heptadien-4-one
• CAS NO: 115819-23-3
• Molecular Weight: 138.21
• Mol File: 115819-23-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-2,5-dimethyl-2,5-heptadien-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2,5-dimethyl-2,5-heptadien-4-one(115819-23-3)
• EPA Substance Registry System: (E)-2,5-dimethyl-2,5-heptadien-4-one(115819-23-3)

Safety Data

• Hazardous Substances Data: 115819-23-3(Hazardous Substances Data)

Relevant articles and documents

172. β-Cleavage of Bis(homoallylic) Potassium Alkoxides. Two-Step Preparation of Propenyl Ketones from Carboxylic Esters. Synthesis of ar-Turmerone, α-Damascone, β-Damascone, and β-Damascenone

The transformation of 36 bis(homoallylic) alcohols VII to alkenones IX and X via β-cleavage of their potassium alkoxides VIIa in HMPA has been investigated (cf.Scheme 2).These studies have established an order of β-cleavage for 2-propenyl, 1-methyl-2-propenyl, 2-methyl-2-propenyl, 1,1-dimethyl-2-propenyl, and benzyl groups in alkoxides 49a-56a and have allowed a comparison between the β-cleavage reaction and the oxy-Cope rearrangement in alkoxides 74a-83a.As illustrative synthetic applications, a two-step preparation of propenyl ketones 15-42 from carboxylic esters is described, together with syntheses of ar-turmerone (48), α-damascone ((E)-71), β-damascone ((E)-109), and β-damascenone ((E)-111).