115869-06-2

Basic information

• Product Name: 1,1-bis(trifluoroacetoxy)cyclohexane
• Synonyms: 1,1-bis(trifluoroacetoxy)cyclohexane
• CAS NO: 115869-06-2
• Molecular Weight: 308.177
• Mol File: 115869-06-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,1-bis(trifluoroacetoxy)cyclohexane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-bis(trifluoroacetoxy)cyclohexane(115869-06-2)
• EPA Substance Registry System: 1,1-bis(trifluoroacetoxy)cyclohexane(115869-06-2)

Safety Data

• Hazardous Substances Data: 115869-06-2(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 371-90-4 1,1-difluorocyclohexane 
• 108-94-1 cyclohexanone 
• 407-25-0 trifluoroacetic anhydride 

Relevant articles and documents

Practical synthesis of gem-difluorides from cyclohexanone: Synthesis of gem-bistrifluoroacetates and their reactions with fluoride nucleophiles

Formation of ketone acylals bearing trihaloacetoxy groups and their nucleophilic geminal disubstitution by fluoride ions were investigated. Cyclohexanone reacted with trifluoroacetic anhydride without catalyst to give gem-bistrifluoroacetates via a concerted bimolecular reaction. Treatment with hydrogen fluoride under mild conditions efficiently yielded the corresponding gem-difluorides. In this reaction process, trifluoroacetic acid was recovered and converted to trifluoroacetic anhydride using P2O5. Since gem-difluorides were derived from ketones, HF and P2O5, this constitutes a practical synthesis of gem-difluorides.