115884-67-8

Basic information

• Product Name: (±)-4-(dimethyl(phenyl)silyl)but-3-yn-2-ol
• Synonyms: (±)-4-(dimethyl(phenyl)silyl)but-3-yn-2-ol
• CAS NO: 115884-67-8
• Molecular Weight: 204.344
• Mol File: 115884-67-8.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: (±)-4-(dimethyl(phenyl)silyl)but-3-yn-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (±)-4-(dimethyl(phenyl)silyl)but-3-yn-2-ol(115884-67-8)
• EPA Substance Registry System: (±)-4-(dimethyl(phenyl)silyl)but-3-yn-2-ol(115884-67-8)

Safety Data

• Hazardous Substances Data: 115884-67-8(Hazardous Substances Data)

Upstream product

• 768-33-2 phenyldimethylsilyl chloride 
• 2028-63-9 but-3-yn-2-ol 
• 263914-55-2 (+/-)-2-[3-(dimethylphenylsilyl)-1-methyl-2-propynyloxy]tetrahydropyran 
• 17156-64-8 (dimethylphenylsilyl)acetylene 
• 75-07-0 acetaldehyde 

Downstream Products

• 142697-17-4 (S)-4-(dimethyl(phenyl)silyl)-but-3-yn-2-ol 
• 142611-82-3 (R)-4-(dimethyl(phenyl)silyl)-but-3-yn-2-yl acetate 
• 263914-87-0 (R)-4-(dimethyl(phenyl)silyl)-but-3-yn-2-ol 
• 144945-73-3 4-(Dimethyl-phenyl-silanyl)-hex-5-en-2-one 
• 144945-86-8 4-(Dimethyl-phenyl-silanyl)-5-methyl-hex-5-en-2-one 
• 144945-87-9 (Z)-4-(Dimethyl-phenyl-silanyl)-dec-5-en-2-one 
• 144945-88-0 (2R,4R,6S)-4-(Dimethyl-phenyl-silanyl)-decane-2,6-diol 
• 144945-76-6 (2R,3R)-3-(Dimethyl-phenyl-silanyl)-2-methyl-hexane-1,5-diol 
• 144945-76-6 (2S,3R)-3-(Dimethyl-phenyl-silanyl)-2-methyl-hexane-1,5-diol 
• 263914-85-8 C₁₄H₁₈O₂Si 
• 1613149-65-7 methyl 3-(dimethyl(phenyl)silyl)hexa-3,4-dienoate 
• 1428676-20-3 (S)-5-[dimethyl(phenyl)silyl]-6-methyl-2-tosyl-8-(trimethylsilyl)-1,2,3,4-tetrahydrocyclopenta[c]azepin-7(6H)-one 
• 1428676-21-4 (S)-8-cyclopropyl-5-[dimethyl(phenyl)silyl]-6-methyl-2-tosyl-1,2,3,4-tetrahydrocyclopenta[c]azepin-7(6H)-one 
• 1428676-16-7 (S)-5-[dimethyl(phenyl)silyl]-6-methyl-8-(thiophen-2-yl)-2-tosyl-1,2,3,4-tetrahydrocyclopenta[c]azepin-7(6H)-one 

Relevant articles and documents

Enantioselective NiH/Pmrox-Catalyzed 1,2-Reduction of α,β-Unsaturated Ketones

The enantioselective 1,2-reduction of α,β-unsaturated ketones was achieved using a NiH catalyst in the presence of pinacolborane. This mild process represents a general method to access a wide variety of structurally diverse α-chiral allylic alcohols in excellent yields and enantioselectivity, as well as very high levels of ambidoselectivity for 1,2- over 1,4-reduction. Furthermore, for reactions on a 10 mmol scale, catalyst loadings as low as 0.5 mol % could be employed to deliver product without any detrimental effect on the yield, enantio-, or ambidoselectivity.

Preparation of (Ra)-methyl 3-(dimethyl(phenyl)silyl)hexa-3,4- dienoate

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Preparation and use of enantioenriched Allenylsilanes for the stereoselective synthesis of homopropargylic ethers

Equation Presented A convenient procedure for the synthesis of highly enantioenriched allenylsilanes by Johnson orthoester Claisen rearrangement of 1-silyl propargylic alcohols is described. Allenylsilanes are then used as carbon nucleophiles in three-com