1158997-68-2

Basic information

• Product Name: 5-amino-4-[(4-chlorophenyl)thio]-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-1H-pyrazole-3-carbonitrile
• Synonyms: 5-amino-4-[(4-chlorophenyl)thio]-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-1H-pyrazole-3-carbonitrile
• CAS NO: 1158997-68-2
• Molecular Weight: 463.698
• Mol File: 1158997-68-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-amino-4-[(4-chlorophenyl)thio]-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-1H-pyrazole-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-4-[(4-chlorophenyl)thio]-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-1H-pyrazole-3-carbonitrile(1158997-68-2)
• EPA Substance Registry System: 5-amino-4-[(4-chlorophenyl)thio]-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-1H-pyrazole-3-carbonitrile(1158997-68-2)

Safety Data

• Hazardous Substances Data: 1158997-68-2(Hazardous Substances Data)

Upstream product

• 1142-19-4 4,4'-dichlorodiphenyl disulfide 
• 120068-79-3 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole 

Relevant articles and documents

Iron-catalyzed direct sulfenylation and selenylations of phenylpyrazoles: Synthesis of fipronil derivatives with disulfides promoted by a catalytic amount of iodine

The direct thiolation of phenylpyrazole with disulfide using the FeBr 3/I2 complex as the catalyst in MeCN at 80 °C was reported. With the optimum conditions, several fipronil derivatives of 4-sulfenylpyrazole were synthesized by the reaction of 5-amino-1-[2,6-dichloro- 4-(trifluoromethyl)phenyl-lH-pyrazole-3-arbonitrile (1a) with disulfides (2) in moderate to good yields. The coupling reaction with diaryl diselane also occurred under similar conditions.