115946-46-8Relevant articles and documents
A MILD AND EFFICIENT METHOD FOR THE PREPARATION OF N-TOSYL AMIDES AND LACTAMS
Tanner, David,Somfai, Peter
, p. 613 - 618 (2007/10/02)
N-tosyl amides and lactams can be prepared easily and under mild conditions by the inter- or intramolecular condensation of carboxylic acids and secondary sulfonamides.The coupling reagent used is dicyclohexylcarbodiimide (DCC) in the presence of 4-pyrrolidinopyridine (4-PPY) and the reactions proceed readily, usually in high yield, at room temperature.