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1159687-95-2

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1159687-95-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1159687-95-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,9,6,8 and 7 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1159687-95:
(9*1)+(8*1)+(7*5)+(6*9)+(5*6)+(4*8)+(3*7)+(2*9)+(1*5)=212
212 % 10 = 2
So 1159687-95-2 is a valid CAS Registry Number.

1159687-95-2Downstream Products

1159687-95-2Relevant articles and documents

[35S]GTPγS binding studies of amphiphilic drugs-activated Gi proteins: A caveat

Manetti, Dina,Mannelli, Lorenzo Di Cesare,Dei, Silvia,Guandalini, Luca,Martini, Elisabetta,Banchelli, Martina,Ghelardini, Carla

supporting information; experimental part, p. 2224 - 2229 (2009/12/07)

This paper documents a serious problem met during the testing of Gi protein-activating properties of a new series of synthetic compounds by measuring the induced binding of [35S]GTPγS to different subtypes of Gi protein. The problem arose from the strong affinity between [35S]GTPγS and the tested compounds, that are characterized by several (2-4) positive charges and high lipophilicity. Apparently, such affinity yields insoluble, labelled complexes that, also in the absence of Gi protein, are retained on the filters and give rise to false positive results.

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