1159706-94-1

Basic information

• Product Name: (3,5-diallyl-2,6-dihydroxy-4-methoxyphenyl)(phenyl)methanone
• Synonyms: (3,5-diallyl-2,6-dihydroxy-4-methoxyphenyl)(phenyl)methanone
• CAS NO: 1159706-94-1
• Molecular Weight: 324.376
• Mol File: 1159706-94-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (3,5-diallyl-2,6-dihydroxy-4-methoxyphenyl)(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (3,5-diallyl-2,6-dihydroxy-4-methoxyphenyl)(phenyl)methanone(1159706-94-1)
• EPA Substance Registry System: (3,5-diallyl-2,6-dihydroxy-4-methoxyphenyl)(phenyl)methanone(1159706-94-1)

Safety Data

• Hazardous Substances Data: 1159706-94-1(Hazardous Substances Data)

Upstream product

• 479-21-0 cotoin 
• 106-95-6 allyl bromide 
• 108-73-6 3,5-dihydroxyphenol 
• 98-88-4 benzoyl chloride 

Downstream Products

• 1159706-95-2 (2,6-dihydroxy-4-methoxy-3,5-dipropylphenyl)(phenyl)-methanone 
• 1159707-01-3 4,6-diallyl-2-benzoyl-3-hydroxy-5-methoxy-6-(2-(propan-2-ylidene)pent-4-enyl)cyclohexa-2,4-dienone 
• 1570098-55-3 (3,5-diallyl-2,4,6-trihydroxyphenyl)(phenyl)methanone 

Relevant articles and documents

Pd-Catalyzed Enantioselective Dearomative Allylic Annulation to Access PPAPs Analogues

Polycyclic polyprenylated acylphloroglucinols (PPAPs) share a common bicyclo[3.3.1]alkenone core structure and attract numerous attention from synthetic organic chemists due to their fascinating biological properties and associated synthetic challenges. We present herein that Pd-phosphoramidite catalysts promote the enantioselective dearomative allylic annulation reaction between allyl desoxyhumulones and allylic dicarbonates, affording PPAPs analogues in good yields and enantioselectivities. The reaction likely proceeds through two-step dearomative allylation by Pd, and the C-allylation pathway is the dominant mechanistic model.

Asymmetric, stereodivergent synthesis of (-)-clusianone utilizing a biomimetic cationic cyclization

We report a stereodivergent, asymmetric total synthesis of (-)-clusianone in six steps from commercial materials. We implement a challenging cationic cyclization forging a bond between two sterically encumbered quaternary carbon atoms. Mechanistic studies point to the unique ability of formic acid to mediate the cyclization forming the clusianone framework. Aim for selectivity: (-)-Clusianone was produced by a stereodivergent asymmetric total synthesis in six steps from commercial materials. The synthesis utilizes a challenging formic acid-mediated cationic cyclization forging a bond between two sterically encumbered quaternary carbon atoms.

Manganese(III)-mediated transformations of phloroglucinols: A formal oxidative [4 + 2] cycloaddition leading to bicyclo[2.2.2]octadiones

Manganese(III)-mediated oxidative transformations of dearomatized phloroglucinol (1,3,5-trihydroxybenzene) derivatives are reported. A number of cyclization modes have been observed, including polycyclization to afford bicyclo[2.2.2]octadiones via a forma