116-44-9 Usage
General Description
Benzenesulfonamide, 4-amino-N-2-pyrazinyl-, also known as pyrazinamide, is a medication used in the treatment of tuberculosis. It works by disrupting the production of RNA and DNA in the bacteria that cause tuberculosis, ultimately leading to their death. Pyrazinamide is classified as a first-line anti-tuberculosis medication and is often used in combination with other drugs to effectively treat the disease. It is typically taken orally and has been shown to be effective in both drug-sensitive and drug-resistant cases of tuberculosis. However, it may cause side effects such as liver damage, gastrointestinal disturbances, and skin rashes in some individuals. Overall, pyrazinamide is an essential component in the treatment of tuberculosis and plays a crucial role in combating the spread of the disease.
Check Digit Verification of cas no
The CAS Registry Mumber 116-44-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,1 and 6 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 116-44:
(5*1)+(4*1)+(3*6)+(2*4)+(1*4)=39
39 % 10 = 9
So 116-44-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H10N4O2S/c11-8-1-3-9(4-2-8)17(15,16)14-10-7-12-5-6-13-10/h1-7H,11H2,(H,13,14)
116-44-9Relevant articles and documents
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Sausville,Spoerri
, p. 3153 (1941)
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3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF
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Paragraph 00294, (2017/10/06)
The present invention provides compounds, compositions thereof, and methods of using the same.