1160478-47-6

Basic information

• Product Name: C₁₅H₁₆BrClN₂O₃
• Synonyms: C₁₅H₁₆BrClN₂O₃
• CAS NO: 1160478-47-6
• Molecular Weight: 387.661
• Mol File: 1160478-47-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₁₆BrClN₂O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₁₆BrClN₂O₃(1160478-47-6)
• EPA Substance Registry System: C₁₅H₁₆BrClN₂O₃(1160478-47-6)

Safety Data

• Hazardous Substances Data: 1160478-47-6(Hazardous Substances Data)

Upstream product

• 302821-62-1 ethyl 4-(4-chlorophenyl)-1,6-dimethyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 

Downstream Products

• 1414778-26-9 ethyl 4-(4-chlorophenyl)-6-({[3-cyano-4-(2-furyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl]thio}methyl)-1-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 1414778-30-5 ethyl 4-(4-chlorophenyl)-6-({[3-cyano-4-(4-methylphenyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl]thio}methyl)-1-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 

Relevant articles and documents

The Thorpe-Ziegler-type reaction of 3-cyanopyridine-2(1H)-thiones with Biginelli 6-bromomethyl-3,4-dihydropyrimidin-2(1H)-ones: Cascade assembling of tetra- and pentacyclic heterocyclic scaffolds

3-Cyanopyridine-2(1H)-thiones have been shown to react with Biginelli-type ethyl 4-aryl-6-(bromomethyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates upon heating in DMF giving rise to ethyl 4-aryl-6-{[(3-cyanopyridin-2-yl)thio] methyl}-2-oxo-1,2,3,4-