1160506-38-6 Usage
Chemical compound
1-Phenylnaphthalen-2-yl trifluoromethanesulfonate is a chemical compound commonly used as a synthetic reagent in organic chemistry.
Tertiary butyl ester
It is a tertiary butyl ester of trifluoromethanesulfonic acid, which provides stability and ease of handling.
Triflate derivative
It is a triflate derivative of 1-phenylnaphthalene, a structural isomer of 2-phenylnaphthalene, known for its ability to act as an excellent leaving group in various chemical reactions.
Reactivity
It is valuable in a variety of chemical reactions such as nucleophilic aromatic substitution, Suzuki cross-coupling, and palladium-catalyzed reactions due to its ability to act as a leaving group.
Industrial applications
It is widely used in the pharmaceutical industry for the synthesis of various drugs and biologically active molecules, as well as in the production of agrochemicals and advanced materials.
Importance
1-Phenylnaphthalen-2-yl trifluoromethanesulfonate plays a crucial role in the advancement of organic chemistry and the development of new chemical compounds with important industrial and medicinal applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1160506-38-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,6,0,5,0 and 6 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1160506-38:
(9*1)+(8*1)+(7*6)+(6*0)+(5*5)+(4*0)+(3*6)+(2*3)+(1*8)=116
116 % 10 = 6
So 1160506-38-6 is a valid CAS Registry Number.
1160506-38-6Relevant articles and documents
Br?nsted acid-catalysed hydroarylation of unactivated alkynes in a fluoroalcohol-hydrocarbon biphasic system: Construction of phenanthrene frameworks
Takahashi, Ikko,Fujita, Takeshi,Shoji, Noriaki,Ichikawa, Junji
supporting information, p. 9267 - 9270 (2019/08/08)
Transition metal-free hydroarylation of unactivated alkynes was achieved by combining a Br?nsted acid catalyst and a two-phase solvent system consisting of 1,1,1,3,3,3-hexafluoropropan-2-ol (HFIP) and cyclohexane. This protocol is applicable to a wide variety of 2-alkynylbiaryls which leads to the synthesis of substituted phenanthrenes via 6-endo-selective ring closure. The biphasic system achieves highly efficient ring closure by appropriate separation of cationic intermediates from neutral compounds. The vinyl carbocation intermediates are stabilised in the HFIP phase, while the substrates and products are distributed in the cyclohexane phase to suppress intermolecular side reactions.
