1160757-30-1 Usage
Description
(2-(trimethylsilyl)phenyl)boronic acid is a boronic acid derivative with the chemical formula (C6H5)(CH3)3SiB(OH)2. It features a trimethylsilyl group attached to a phenyl ring, making it a versatile reagent in organic synthesis.
Used in Organic Synthesis:
(2-(trimethylsilyl)phenyl)boronic acid is used as a reagent for the Suzuki-Miyaura cross-coupling reaction, a widely used method for forming carbon-carbon bonds. This reaction is essential for constructing complex molecular structures in organic chemistry.
Used in Protecting Groups:
In organic reactions, the trimethylsilyl group of (2-(trimethylsilyl)phenyl)boronic acid can serve as a protecting group, allowing for selective synthesis of specific products. This selective synthesis is crucial for the development of complex organic compounds and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 1160757-30-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,6,0,7,5 and 7 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1160757-30:
(9*1)+(8*1)+(7*6)+(6*0)+(5*7)+(4*5)+(3*7)+(2*3)+(1*0)=141
141 % 10 = 1
So 1160757-30-1 is a valid CAS Registry Number.
1160757-30-1Relevant articles and documents
Rhodium-catalyzed coupling of 2-silylphenylboronic acids with alkynes leading to benzosiloles: Catalytic cleavage of the carbon-silicon bond in trialkylsilyl groups
Tobisu, Mamoru,Onoe, Masahiro,Kita, Yusuke,Chatani, Naoto
supporting information; experimental part, p. 7506 - 7507 (2009/10/17)
(Chemical Equation Presented) The reaction of 2-(trimethylsilyl) phenylboronic acid with alkynes in the presence of a rhodium catalyst affords benzosilole derivatives. The arylvinylrhodium intermediate undergoes formal substitution at a silicon center, resulting in the cleavage of a robust silicon-methyl bond in the trimethylsilyl group.
