1160790-18-0

Basic information

• Product Name: 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine
• Synonyms: [1,2,4]Triazolo[1,5-a]pyridine-6-boronic acid pinacol ester 95%;6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine;[1,2,4]Triazolo[1,5-a]pyridine-6-boronic acid pinacol ester;[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLBORONIC ACID PINACOL ESTER
• CAS NO: 1160790-18-0
• Molecular Formula: C₁₂H₁₆BN₃O₂
• Molecular Weight: 245
• Mol File: 1160790-18-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 109-114°C
• Appearance: /
• Density: 1.19±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 2.71±0.30(Predicted)
• CAS DataBase Reference: 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine(1160790-18-0)
• EPA Substance Registry System: 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine(1160790-18-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 1160790-18-0(Hazardous Substances Data)

Usage

General Description

6-(4,4,5,5-tetramethyl-1,3,2-Dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine is a chemical compound with potential applications in the fields of pharmaceuticals, agrochemicals, and material science. It contains a boron-containing group and a pyridine ring, both of which are important structural elements in many biologically active compounds. The compound has been identified as a key building block for the synthesis of various drugs and agrochemicals due to its ability to interact with specific biological targets. Additionally, its unique molecular structure makes it a promising candidate for the development of new materials with specific electronic, optical, or magnetic properties. Overall, 6-(4,4,5,5-tetramethyl-1,3,2-Dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine has the potential to have a significant impact in various scientific and industrial applications.

Upstream product

• 356560-80-0 6-bromo[1,2,4]triazolo[1,5-a]pyridine 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1210047-66-7 methyl 5-methoxy-2-((3-methyl-1-(2-methylphenyl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-pyrazol-5-yl)amino)benzoate 
• 4931-24-2 6-methyl-[1,2,4]triazolo[1,5-a]pyridine 

Relevant articles and documents

FUSED RING DERIVATIVE AS A2A RECEPTOR INHIBITOR

Disclosed are a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, and an application of the compound or slat in preparation of drugs for treating diseases related to an A2A receptor.

2-PYRIDYL SUBSTITUTED IMIDAZOLES AS ALK5 AND/OR ALK4 INHIBITORS

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ANTIBACTERIAL CONDENSED THIAZOLES

Compound of formula (I) have antibacterial activity: wherein: m is 0 or 1; Q is hydrogen or cyclopropyl; AIk - is an optionally substituted, divalent C1-C6 alkylene, alkenylene or alkynylene radical which may contain an ether (-0-), thioether (-S-) or amino (-NR)- link, wherein R is hydrogen, -CN or C1-C3 alky!; X is -C(=O)NR6-, or -C(=O)O- wherein R6 is hydrogen, optionally substituted C1-C6 alkyl, C2-C6 alkenyl or C2-C6 alkynyl; Z1 is -N= or -CH= Z2 is -N= or -C(R1)=; R1 is hydrogen, methyl, ethyl, ethenyl, ethynyl, methoxy, mercapto, mercaptomethyl halo, fully or partially fluorinated (C1-C2)alkyl, (C1-C2JaIkOXy or (C1-C2)alkylthio, nitro, or nitrile (-CN); R2 is a group Q1 -[Alk1]q-Q2 -, wherein q is 0 or 1; AIkl is an optionally substituted, divalent, straight chain or branched C1-C6 alkylene, or C2-C6 alkenylene or C2-C6 alkynylene radical which may contain or terminate in an ether (-O-), thioether (-S-) or amino (-NR)- link; Q2 is an optionally substituted divalent monocyclic carbocyclic or heterocyclic radical having 5 or 6 ring atoms or an optionally substituted divalent bicyclic carbocyclic or heterocyclic radical having 9 or 10 ring atoms; Q1 is hydrogen, an optional substituent or an optionally substituted carbocyclic or heterocyclic radical having 3-7 ring atoms