116083-32-0

Basic information

• Product Name: 21-carboxymethylthio-4-pregnene-3,20-dione
• Synonyms: 21-carboxymethylthio-4-pregnene-3,20-dione
• CAS NO: 116083-32-0
• Molecular Weight: 404.571
• Mol File: 116083-32-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 21-carboxymethylthio-4-pregnene-3,20-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 21-carboxymethylthio-4-pregnene-3,20-dione(116083-32-0)
• EPA Substance Registry System: 21-carboxymethylthio-4-pregnene-3,20-dione(116083-32-0)

Safety Data

• Hazardous Substances Data: 116083-32-0(Hazardous Substances Data)

Upstream product

• 20576-46-9 11-deoxy-21-iodocorticosterone 
• 68-11-1 mercaptoacetic acid 

Relevant articles and documents

SYNTHESIS OF 21-THIOALKANOIC ACIDS OF CORTICOSTEROIDS

The 21-thioalkanoic acids of corticosteroids were obtained as a result of nucleophilic substitution in the reaction of the 21-sulfonic esters and 21-halogeno derivatives of corticosteroids with the thiolates of mercaptoalkanoic acids.The thiolates were synthesized by the action of bases on the corresponding mercaptoalkanoic acids.The 21-thioalkanoic acids of the corticosteroids were also obtained by the reaction of the 21-chloro and 21-bromo derivatives of the corticosteroids with mercaptoalkanoic acids in dipolar aprotic solvents.